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Ghrelin de John N. Abelson

Ghrelin: Methods in Enzymology, cartea 514

John N. Abelson, Kenji Kangawa
en Limba Engleză Hardback – 8 noi 2012
This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. The volume covers ghrelin, and has chapters on such topics as orphan gpcrs and methods for identifying their ligands, ghrelin o-acyltransferase assays and inhibition, and thermogenic characterization of ghrelin receptor null mice.


  • Contains quality chapters authored by leaders in the field
  • Has chapters on such topics as orphan gpcrs and methods for identifying their ligands, ghrelin o-acyltransferase assays and inhibition, and thermogenic characterization of ghrelin receptor null mice
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Specificații

ISBN-13: 9780123812728
ISBN-10: 0123812720
Pagini: 512
Dimensiuni: 152 x 229 mm
Greutate: 0.84 kg
Editura: ELSEVIER SCIENCE
Seria Methods in Enzymology

Public țintă

Biochemists, biophysicists, molecular biologists, analytical chemists, and physiologists

Cuprins

1. History of GHS and ghrelin 2. History To The Discovery Of Ghrelin 3. Orphan Gpcrs And Methods For Identifying Their Ligands 4. Purification Of Rat And Human Ghrelins 5. Variety of Acyl Modifications in Mammalian Ghrelins 6. Determination Of Non-Mammalian Ghrelin
Molecular forms of ghrelin and Measuring of the concentrations 7. Morphological Analysis Of Ghrelin Neurons In The Hypothalamus 8. High-Performance Liquid Chromatography Analysis Of Hypothalamic Ghrelin 9. Standard Sample Collections For Blood Ghrelin Measurements
Enzymes for processing of ghrelin 10. From Ghrelin to Ghrelin’s O Acyl Transferase 11. Enzymatic Characterization Of Goat, Ghrelin O-Acyltransferase 12. The Study Of Ghrelin Deacylation Enzymes
Synthesis of ghrelin agonists and antagonists 13. Synthesis Of Ghrelin Chemical Synthesis And Semi-Synthesis For Large-Scale Preparation Of Modified Peptides 14. Ghrelin O-Acyltransferase Assays And Inhibition
Action of ghrelin 15. Model-Based Evaluation Of Growth Hormone Secretion 16. Ghrelin In The Control Of Energy, Lipid And Glucose Metabolism 17. Ghrelin And The Vagus Nerve 18. Measurement of amp-activated protein kinase (ampk) activity and expression In response to ghrelin 19. Ghrelin And Gastrointestinal Movement 20. Ghrelin Acylation By Ingestion Of Medium-Chain Fatty Acids 21. Islet ß-cell Ghrelin Signaling For Inhibition Of Insulin Secretion 22. Rikkunshito As A Ghrelin Enhancer
Tg and KO mice of ghrelin 23. Thermogenic Characterization Of Ghrelin Receptor Null Mice 24. Transgenic Mice Over-Expressing Ghrelin Or Ghrelin Analog
Clinical application of ghrelin 25. Therapeutic Potential Of Ghrelin In Restricting-Type Anorexia Nervosa 26. Clinical Application Of Ghrelin For Chronic Respiratory Diseases 27. Clinical Trial Of Ghrelin Synthesis Administration For Upper Gi Surgery