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Health Outcomes in a Foreign Land : A Role for Epigenomic and Environmental Interaction

Autor Bernard Kwabi-Addo
en Limba Engleză Paperback – 12 mai 2018
This stimulating volume uses multiple lenses to analyze the complex causes of health disparities affecting minorities, in particular African Americans, and explains how this knowledge can be used to reduce their destructive effects. Pinpointing genetic, non-genetic, and epigenetic factors underlying health conditions common to the population—including heart disease, hypertension, diabetes, and cancer—the author traces intricate links among these factors in the current environmental and social context. The section on non-genetic factors in health disparities, such as social determinants and health behaviors, adds depth to the ongoing discourse on public health and health policy objectives. And the chapters on gene/environment interactions outline the vast potential for developing new multidisciplinary frontiers in shrinking health inequities and personalizing care.
Included in the coverage:

 
  • The African diaspora and disease-specific disparities
  • The genetic basis to health disparities
  • The role of epigenetics
  • Economic factors and health
  • Psychological issues and how they affect disparities
  • Gene-environment interactions in health disparities
  • Race, a biological or social concept
Compelling and accessible, Health Outcomes in a Foreign Land will challenge and inspire medical students, epidemiologists, public health professionals, biomedical research scientists, and social scientists to go farther in their work. A wider audience would include policymakers, government officials, nurses, physicians, lawyers, economists, community outreach investigators, and interested general readers. 
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Specificații

ISBN-13: 9783319857664
ISBN-10: 3319857665
Pagini: 324
Ilustrații: XXVI, 324 p. 16 illus.
Dimensiuni: 155 x 235 mm
Greutate: 0.49 kg
Ediția:Softcover reprint of the original 1st ed. 2017
Editura: Springer International Publishing
Colecția Springer
Locul publicării:Cham, Switzerland

Cuprins


Disease-specific disparities of the African diaspora.- The genetic basis to health disparity.- The role of epigenetics.- Economic factors and health.- Social determinants.- Behavior and health disparities.-  Health literacy deficits.- The impact of culture.-   Psychological issues and how they affect disparities.- Gene-environment interactions in health disparities.-  Race, a biological or social concept.- Translating health disparities.
 


Recenzii

“This is a multilayered, interdisciplinary survey of genetic and non-genetic influences on health inequities, mainly among Americans of African descent. … it is a highly readable epidemiological synopsis from an under-represented viewpoint — that of a recent West African immigrant confronting a country founded by immigrants. As such, it offers a new, potential source of insights.” (Fatimah Jackson, nature.com, July, 2018)

Notă biografică

Bernard Kwabi-Addo, PhD, is an associate professor of Biochemistry and Molecular Biology and the Principal Investigator of the Prostate Cancer Research Laboratory at Howard University in Washington, D.C., and an adjunct associate professor of Oncology at Johns Hopkins Medical School in Baltimore, Maryland. His research work included receptor tyrosine kinase signaling in prostate cancer. More recently, Dr. Kwabi-Addo is investigating the role of epigenetic changes in prostate cancer etiology/progression with an emphasis on understanding the contribution of epigenetic changes as well as gene-environmental interaction in cancer disparities.

Dr. Kwabi-Addo graduated from Queen Mary and Westfield College at University of London (where he received a PhD studying site-directed gene targeting in mammalian cells using the bacteriophage Cre-loxP recombination system as a tool) and University College London in England, and University of Dundee in Scotland. He trained at Baylor College of Medicine in Houston, Texas, in cancer biology, specifically in prostate cancer research. Dr. Kwabi-Addo has published scientific articles in journals including Nature Genetics, PNAS, Cancer Research, Prostate, and Epigenetics. His book, Cancer Causes and Controversies: Understanding Risk Reduction and Prevention, was published by Praeger in 2011. He lives in Northern Virginia with his wife, Gertrude, a financial analyst, and their three sons, Benjamin, Joshua, and David.

Textul de pe ultima copertă

This stimulating volume uses multiple lenses to analyze the complex causes of health disparities affecting minorities, in particular African Americans, and explains how this knowledge can be used to reduce their destructive effects. Pinpointing genetic, non-genetic, and epigenetic factors underlying health conditions common to the population—including heart disease, hypertension, diabetes, and cancer—the author traces intricate links among these factors in the current environmental and social context. The section on non-genetic factors in health disparities, such as social determinants and health behaviors, adds depth to the ongoing discourse on public health and health policy objectives. And the chapters on gene/environment interactions outline the vast potential for developing new multidisciplinary frontiers in shrinking health inequities and personalizing care.
Included in the coverage:

 
  • The African diaspora and disease-specific disparities
  • The genetic basis to health disparities
  • The role of epigenetics
  • Economic factors and health
  • Psychological issues and how they affect disparities
  • Gene-environment interactions in health disparities
  • Race, a biological or social concept
Compelling and accessible, Health Outcomes in a Foreign Land will challenge and inspire medical students, epidemiologists, public health professionals, biomedical research scientists, and social scientists to go farther in their work. A wider audience would include policymakers, government officials, nurses, physicians, lawyers, economists, community outreach investigators, and interested general readers. 

Caracteristici

Is a one-of-a-kind book in presenting a link between epigenetic and environmental interaction in understanding health disparities among the African diaspora
Discusses multiple ways in which environmental factors can influence health outcomes and reduce risk for different types of diseases
Also discusses how the knowledge of genetic variance in different populations can be explored as biomarkers for disease detection and in precision medicine
Aims to increase understanding of how environmental factors can influence gene expression and health outcomes in different racial and ethnic populations
Includes supplementary material: sn.pub/extras