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Human Identification: The Use of DNA Markers: Contemporary Issues in Genetics and Evolution, cartea 4

Editat de B. Weir
en Limba Engleză Paperback – 3 oct 2013
The ongoing debate on the use of DNA profiles to identify perpetrators in criminal investigations or fathers in paternity disputes has too often been conducted with no regard to sound statistical, genetic or legal reasoning. The contributors to Human Identification: The Use of DNA Markers all have considerable experience in forensic science, statistical genetics or jurimetrics, and many of them have had to explain the scientific issues involved in using DNA profiles to judges and juries. Although the authors hold differing views on some of the issues, they have all produced accounts which pay due attention to the, sometimes troubling, issues of independence of components of the profiles and of population substructures. The book presents the considerable evolution of ideas that has occurred since the 1992 Report of the National Research Council of the U.S.
Audience: Indispensable to forensic scientists, laying out the concepts to all those with an interest in the use of genetic information. The chapters and exhaustive bibliography are vital information for all lawyers who must prosecute or defend DNA cases, and to judges trying such cases.
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Specificații

ISBN-13: 9789401718035
ISBN-10: 9401718032
Pagini: 224
Ilustrații: V, 215 p. 10 illus.
Dimensiuni: 155 x 235 x 12 mm
Greutate: 0.32 kg
Ediția:Softcover reprint of the original 1st ed. 1995
Editura: SPRINGER NETHERLANDS
Colecția Springer
Seria Contemporary Issues in Genetics and Evolution

Locul publicării:Dordrecht, Netherlands

Public țintă

Research

Cuprins

A method for quantifying differentiation between populations at multi-allelic loci and its implications for investigating identity and paternity.- The effect of relatedness on likelihood ratios and the use of conservative estimates.- The effects of inbreeding on DNA profile frequency estimates using PCR-based loci.- Correlation of DNA fragment sizes within loci in the presence of non-detectable alleles.- Inference of population subdivision from the VNTR distributions of New Zealanders.- Conditioning on the number of bands in interpreting matches of multilocus DNA profiles.- Match probability calculations for multi-locus DNA profiles.- Population genetics of short tandem repeat (STR) loci.- Assessing probability of paternity and the product rule in DNA systems.- The forensic debut of the NRC’s DNA report: population structure, ceiling frequencies and the need for numbers.- Applications of the Dirichlet distribution to forensic match probabilities.- The honest scientist’s guide to DNA evidence.- A comparison of tests for independence in the FBI RFLP data bases.- Alternative approaches to population structure.- DNA evidence: wrong answers or wrong questions?.- Subjective interpretation, laboratory error and the value of forensic DNA evidence: three case studies.- Exact tests for association between alleles at arbitrary numbers of loci.- A bibliography for the use of DNA in human identification.