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Immunotherapeutic Strategies for the Treatment of Glioma: Breaking Tolerance to Anti-Cancer Cell-Mediated Immunotherapy

Editat de Christopher Jackson, Michael Lim
en Limba Engleză Hardback – 13 sep 2021
Immunotherapeutic Strategies for the Treatment of Glioma provides a review of the current state of immunotherapy for primary brain tumors. The topic is of interest to patients, clinicians, and researchers alike, particularly given the recent failure of large clinical trials. This book serves as an overview of the most promising approaches in the field and provides a foundation for considering novel and combination therapies moving forward.
The book discusses several types of immunotherapies for glioma, such as peptide, dendritic cell and heat shock protein vaccines; immune checkpoint blockade; myeloid cells as target; oncolytic viruses; and CAR T cell therapy. Additionally, it discusses the mechanisms of immune suppression in patients and immunogenomics.
This volume is a valuable source for cancer researchers, oncologists and several members of biomedical field who are interested in novel strategies to fight glioblastoma.

  • Summarizes the work in immunotherapy for glioma to-date, including the available evidence from preclinical studies and clinical trials
  • Reviews the challenges and successes of the most promising strategies for brain tumor immunotherapy
  • Provides a foundation for considering novel and combination therapies moving forward
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Specificații

ISBN-13: 9780128197554
ISBN-10: 0128197552
Pagini: 190
Dimensiuni: 191 x 235 x 16 mm
Editura: ELSEVIER SCIENCE
Seria Breaking Tolerance to Anti-Cancer Cell-Mediated Immunotherapy


Public țintă

Cancer researchers, medical scientists, clinicians, graduate students

Cuprins

1. Peptide vaccines 2. Dendritic cell vaccines 3. Heat shock protein vaccines 4. Immune checkpoint blockade 5. Targeting myeloid cells in glioblastoma 6. Oncolytic viruses 7. CAR T cell therapy 8. Mechanisms of immune suppression in glioblastoma patients 9. Immunogenomics in glioblastoma