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In vivo Models of HIV Disease and Control: Infectious Agents and Pathogenesis

Editat de Herman Friedman, Steven Specter, Mauro Bendinelli
en Limba Engleză Hardback – 21 dec 2005
An AIDS vaccine is still elusive and HIV treatment continues to develop multidrug resistance at alarming rates. Because of the similarities between HIV and immune deficiency infections in a variety of animals, it is only natural that scientists use these animals as models to study pathogenesis, treatment, vaccine development and many other aspects of HIV.
Part of the series Infectious Agents and Pathogenesis, this volume reviews the immune deficiency virus in a variety of hosts. Pathogenesis, vaccine and drug development, epidemiology, and the natural history of the monkey, mouse, cat, cow, horse, and other animal viruses are detailed and compared to HIV. Also included are chapters on the history and future of animal models, as well as a chapter on ethical and safety considerations in using animal models for AIDS studies.
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Specificații

ISBN-13: 9780387257402
ISBN-10: 0387257403
Pagini: 436
Ilustrații: XVIII, 436 p.
Dimensiuni: 155 x 235 x 25 mm
Greutate: 0.81 kg
Ediția:2006
Editura: Springer Us
Colecția Springer
Seria Infectious Agents and Pathogenesis

Locul publicării:New York, NY, United States

Public țintă

Research

Cuprins

Historical Perspective.- Animal Model Systems of HIV-Diseases.- Chemokines and Their Receptors and the Neuropathogenesis of HIV-1 Infection.- SCID Mice Transplanted With Human Cells as Small Animal Models in AIDS Research.- SIV as a Model for AIDS Pathogenesis Studies.- SIV Infection of Macaques as a Model for AIDS Drug Studies.- FIV as a Model for HIV: An Overview.- FIV as a Model for AIDS Pathogenesis Studies.- Drugs of Abuse, AIDS, and the FIV Model.- FIV as a Model for AIDS Vaccine Studies.- FIV as a Model for HIV Treatment.- Equine Infectious Anemia Virus as a Model for Lentiviral Pathogenesis.- Studies of the Structure of Caprine Arthritis-Encephalitis Virus Surface Envelope Glycoprotein.- Ethical Issues in the Use of Animal Models of Infection and Some Practical Refinements.- Future Perspectives.

Caracteristici

This is the first and only comprehensive review volume describing the various immunodeficiency virus diseases in animal models, especially as related to the human AIDS situation Includes supplementary material: sn.pub/extras