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Infection, Immune Homeostasis and Immune Privilege: Birkhäuser Advances in Infectious Diseases

Editat de Joan Stein-Streilein
en Limba Engleză Paperback – 9 aug 2014
Organs and tissues that can tolerate little or no inflammation have developed multiple overlapping mechanisms of immune protection in the absence of inflammation. These areas have been designated “immune-privileged sites” by Peter Medawar and include the central nervous system, eye, reproductive tract, testis and possibly the liver. Mechanisms of immune homeostasis found in less immune-regulated organs are often evident in the immune privileged sites and vice versa. It is important that the non-inflammatory mechanisms that contribute to immune privilege allow host defense against infectious organisms.
This volume highlights the mechanisms leading to immune privilege in tissues and organs, the deviation of immune responses and the modification of the behavior of the immune cells that manage to cross the blood barriers of tissues, in the context of infection.
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Specificații

ISBN-13: 9783034807975
ISBN-10: 303480797X
Pagini: 168
Ilustrații: XII, 156 p.
Dimensiuni: 155 x 235 x 9 mm
Greutate: 0.25 kg
Ediția:2012
Editura: Springer
Colecția Springer
Seria Birkhäuser Advances in Infectious Diseases

Locul publicării:Basel, Switzerland

Public țintă

Research

Cuprins

Introduction.- The Eye as Immune Privileged Site.- Immune Privilege of the Testis – Meaning, Mechanisms and Manifestations.- The Role of Intrauterine Immune Privilege in Perinatal Infectious Diseases.- The Liver as an Immune Privileged Site.- Immune Homeostasis of the Lung: The Role of Regulatory NKT Cells in Asthma.- Immune Homeostasis of the Gut.

Textul de pe ultima copertă

Organs and tissues that can tolerate little or no inflammation have developed multiple overlapping mechanisms of immune protection in the absence of inflammation. These areas have been designated “immune-privileged sites” by Peter Medawar and include the central nervous system, eye, reproductive tract, testis and possibly the liver. Mechanisms of immune homeostasis found in less immune-regulated organs are often evident in the immune privileged sites and vice versa. It is important that the non-inflammatory mechanisms that contribute to immune privilege allow host defense against infectious organisms.
This volume highlights the mechanisms leading to immune privilege in tissues and organs, the deviation of immune responses and the modification of the behavior of the immune cells that manage to cross the blood barriers of tissues, in the context of infection.

Caracteristici

Connects the knowledge of immune regulation in different tissues Adds insight to readers’ understanding of the “Hygiene hypothesis” Presents basic science aspects relevant for diagnosis and disease management Includes supplementary material: sn.pub/extras