Insulin & Related Proteins — Structure to Function and Pharmacology
Editat de Matthias Federwisch, Markus Leyck Dieken, Pierre De Meytsen Limba Engleză Paperback – 3 oct 2013
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Specificații
ISBN-13: 9789401739566
ISBN-10: 9401739560
Pagini: 272
Ilustrații: XIV, 252 p.
Dimensiuni: 155 x 235 x 14 mm
Greutate: 0.39 kg
Ediția:Softcover reprint of the original 1st ed. 2002
Editura: SPRINGER NETHERLANDS
Colecția Springer
Locul publicării:Dordrecht, Netherlands
ISBN-10: 9401739560
Pagini: 272
Ilustrații: XIV, 252 p.
Dimensiuni: 155 x 235 x 14 mm
Greutate: 0.39 kg
Ediția:Softcover reprint of the original 1st ed. 2002
Editura: SPRINGER NETHERLANDS
Colecția Springer
Locul publicării:Dordrecht, Netherlands
Public țintă
ResearchCuprins
How Insulin Came from Heidelberg to Aachen and Why it Took Five Years.- Insulin at the German Wool Research Institute-Retrospect and Outlook.- Insulin: Sequence, Structure and Function - A Story of Surprises.- The Association/Dissociation Equilibria of Insulin in the Presence of Metal Ions: A Fluorescence Energy Transfer and Circular Dichroism Study.- Self-Association of Insulin Reconsidered.- Self-Association of Insulin Reconsidered.- T-R Transition.- Comparison of Conformational Transitions in Proteins.- Activities of Insulin Analogues at Position A8 are Uncorrelated with Thermodynamic Stability.- Relationships between the Structure of Insulin and its Physiological Effects.- Structure-Function Relationships of Insulin and Insulin-Like Growth factor-I Receptor Binding.- Structural Relationships between Members of the Insulin Receptor Family.- Insulin Interaction with Minimized Receptors and Binding Proteins.- Identification of Susceptibility Loci for Obesity, Insulin Resistance, and Hyperglycemia in a Backcross Model of New Zealand Obese (NZO) and Lean SJL Mice.- Activation Mechanism of Fibroblast Growth Factor Receptor Tyrosine Kinase Revealed by Crystal Structure of Fibroblast Growth Factor Receptor Ectodomain Bound to Fibroblast Growth Factor and Heparin.- IL-6 Type Cytokine Receptor Complexes.- Inhibition of Growth Factor Stimulated Pathways for the Treatment of Prostate Cancer.- Molecular Dynamics Simulations of Carbonmonoxy Myoglobin and Calculations of Heme Circular Dichroism.