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Iron Uptake in Bacteria with Emphasis on E. coli and Pseudomonas: SpringerBriefs in Molecular Science

Editat de Ranjan Chakraborty, Volkmar Braun, Klaus Hantke, Pierre Cornelis
en Limba Engleză Paperback – 3 feb 2013
Iron is essential for the growth of most bacteria because it serves as a cofactor for vital enzymes and for the components of the electron transport chain. Moreover, Iron plays an important role in bacterial pathogenicity; in fact, the iron transport systems in bacteria works as target for designing novel antibiotics. Because iron is not soluble under aerobic conditions, bacteria have had to find ways to overcome iron deficiency. One of them is producing an iron-chelating small organic molecule called siderophore. Indeed, most bacteria and fungi produce structurally and chemically diverse siderophores which are transported back to the cytoplasm using complex energy dependent transport systems. Escherichia coli and Pseudomonas were the first ones to be tested; however, nowadays iron transport systems have been investigated in many other bacteria.
Iron Uptake in Bacteria with Emphasis on E. coli and Pseudomonas reviews the recent advancements in the field of iron transport systems in bacteria. Chapter 1 is dedicated to Dr. Dick van der Helm’s contribution to the field of siderophore biology. It then describes and discusses the structural advances in the components and the mechanism of siderophore mediated iron transport systems in E.coli. Chapter 2 details the variety of iron transport and iron regulatory systems of both gram negative and gram positive bacteria. Finally, chapter 3 describes the iron transport systems of Pseudomonas.
This book is aimed at researchers in the fields of iron metabolism in multiple organisms, and to those who are interested in studying iron transport systems of bacteria. It appeals also to scientists researching structure and function relationship of proteins.
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Specificații

ISBN-13: 9789400760875
ISBN-10: 9400760876
Pagini: 104
Ilustrații: XI, 89 p. 17 illus., 14 illus. in color.
Dimensiuni: 155 x 235 x 5 mm
Greutate: 0.16 kg
Ediția:2013
Editura: SPRINGER NETHERLANDS
Colecția Springer
Seriile SpringerBriefs in Molecular Science, SpringerBriefs in Biometals

Locul publicării:Dordrecht, Netherlands

Public țintă

Research

Cuprins

Ferric Siderophore Transport via Outer Membrane Receptors of Escherichia coli: Structural Advancement and a Tribute to Dr. Dick van der Helm- an ‘Ironman’ of Siderophore Biology.- The Tricky Ways Bacteria Cope with Iron Limitation.- Iron Transport Systems and Iron Homeostasis in Pseudomonas.

Caracteristici

Presents the state-of-the-art research in the field of iron transport systems in bacteria Includes supplementary material: sn.pub/extras