Covering the period from the 1930s to the 1980s, Bill O'Reilly and Martin Dugard trace the prohibition-busting bank robbers of the Depression Era, such as John Dillinger, Bonnie & Clyde, Pretty Boy Floyd and Baby-Face Nelson. In addition, the authors highlight the creation of the Mafia Commission, the power struggles within the 'Five Families', the growth of the FBI under J. Edgar Hoover, the mob battles to control Cuba, Las Vegas and Hollywood, as well as the personal war between the U.S. Attorney General Bobby Kennedy and legendary Teamsters boss Jimmy Hoffa.