Lipoprotein(a): Contemporary Cardiology
Editat de Karam Kostner, Gerhard M. Kostner, Peter P. Tothen Limba Engleză Paperback – 5 mar 2024
Lipoprotein(a) [Lp(a)] is a unique lipoprotein that has emerged as an independent risk factor for cardiovascular vascular disease. Data from case control, epigenetic and mendelian randomization studies indicate that people with elevated Lp(a) have a two-fold to four-fold increased risk of cardiovascular events compared to people with low Lp(a) levels. Despite this risk, awareness of Lp(a) is still very low among health care providers. Even cardiologists often overlook Lp(a), in part because Lp(a) is not as well-understood as other risk factors and treatment options are still very limited.
This book offers an authoritative and comprehensive overview of Lipoprotein(a). It provides an in-depth review of all aspects of Lp(a), from pathophysiology to metabolism. Chapters offer the reader a contemporary view of the important roles of Lp(a) as a risk factor for cardiovascular disease. In addition, this volume discusses the clinical implications of elevated Lp(a) and current and future therapies. Lipoprotein(a) is an essential resource for physicians, medical students, residents, fellows, and allied health professionals in lipidology, cardiology, endocrinology, pharmacotherapy, and health promotion and disease prevention.
This book offers an authoritative and comprehensive overview of Lipoprotein(a). It provides an in-depth review of all aspects of Lp(a), from pathophysiology to metabolism. Chapters offer the reader a contemporary view of the important roles of Lp(a) as a risk factor for cardiovascular disease. In addition, this volume discusses the clinical implications of elevated Lp(a) and current and future therapies. Lipoprotein(a) is an essential resource for physicians, medical students, residents, fellows, and allied health professionals in lipidology, cardiology, endocrinology, pharmacotherapy, and health promotion and disease prevention.
Toate formatele și edițiile | Preț | Express |
---|---|---|
Paperback (1) | 1001.96 lei 38-44 zile | |
Springer International Publishing – 5 mar 2024 | 1001.96 lei 38-44 zile | |
Hardback (1) | 1424.34 lei 38-44 zile | |
Springer International Publishing – 4 mar 2023 | 1424.34 lei 38-44 zile |
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Specificații
ISBN-13: 9783031245770
ISBN-10: 3031245776
Pagini: 443
Ilustrații: XVII, 443 p. 92 illus., 76 illus. in color.
Dimensiuni: 155 x 235 mm
Ediția:2023
Editura: Springer International Publishing
Colecția Humana
Seria Contemporary Cardiology
Locul publicării:Cham, Switzerland
ISBN-10: 3031245776
Pagini: 443
Ilustrații: XVII, 443 p. 92 illus., 76 illus. in color.
Dimensiuni: 155 x 235 mm
Ediția:2023
Editura: Springer International Publishing
Colecția Humana
Seria Contemporary Cardiology
Locul publicării:Cham, Switzerland
Cuprins
60 years of Lp(a) research-From Ouchterlonys double diffusion to a significant risk factor for CHD.- Lp(a) structure and composition.- Genetics of Lipoprotein(a).- Lp(a) metabolism.- Contemporary aspects of Lp(a) metabolism and therapies based on tracer kinetic methods.- Role of Proprotein Convertase Subtilisin Kexin type 9 in Lipoprotein(a) Metabolism.- The Role of Cell Surface Receptors in Lp(a) Metabolism.- Physiological Roles And Functions Of Lipoprotein(a).- The role of Lp(a) in Atherosclerosis: An overview.- Role of macrophages in Lp(a) pathophysiology.- Thrombosis, Inflammation and Lipoprotein(a): Clinical Implications .- The role of the kidney in Lp(a) physiology and pathophysiology.- Lp(a) as a cardiovascular risk factor.- Lp(a) and aortic valve stenosis, stroke, and other non-coronary cardiovascular diseases.- Lp(a) in cardiovascular disease: Evidence from Large Epidemiological Studies.- Lipoprotein(A) And Immunity.- When to measure Lp(a) .- Measurement of Lipoprotein (a) in the Clinical Laboratory.- Standardization of analytical methods for the measurement of Lipoprotein(a): bridging past and future initiatives.- Establishing an SI-traceable Reference Measurement System for Lp(a), based on Quantitative Protein Mass Spectrometry and Molar Units.- Compounds that impact Lp(a) concentrations.- Antisense oligonucleotide therapy to treat elevated lipoprotein(a).- Lipoprotein apheresis for reduction of Lipoprotein(a).- Elevated Lp(a) - Why Should I Test For It, If I Cannot Treat It? A Patient’s Perspective .- Burning unanswered questions Therapy.
Notă biografică
Karam Kostner, MD, Ph.D., FRACP, FCSANZ
Brisbane, Australia
Baltimore, Maryland USA
Associate Professor of Medicine
University of Queensland and Mater HospitalBrisbane, Australia
Gerhard M. Kostner, Ph.D.
Graz, AustriaEmeritus Professor of Biochemistry and Molecular Biology
Medical University of Graz, AustriaPeter P. Toth, M.D. , PhD, FAHA, FESC, FACC
Adjunct Professor of Medicine
Adjunct Professor of Medicine
Division of Cardiology
Johns Hopkins University School of MedicineBaltimore, Maryland USA
Textul de pe ultima copertă
Lipoprotein(a) [Lp(a)] is a unique lipoprotein that has emerged as an independent risk factor for cardiovascular vascular disease. Data from case control, epigenetic and mendelian randomization studies indicate that people with elevated Lp(a) have a two-fold to four-fold increased risk of cardiovascular events compared to people with low Lp(a) levels. Despite this risk, awareness of Lp(a) is still very low among health care providers. Even cardiologists often overlook Lp(a), in part because Lp(a) is not as well-understood as other risk factors and treatment options are still very limited.
This book offers an authoritative and comprehensive overview of Lipoprotein(a). It provides an in-depth review of all aspects of Lp(a), from pathophysiology to metabolism. Chapters offer the reader a contemporary view of the important roles of Lp(a) as a risk factor for cardiovascular disease. In addition, this volume discusses the clinical implications of elevated Lp(a) and current and future therapies.
Lipoprotein(a) is an essential resource for physicians, medical students, residents, fellows, and allied health professionals in lipidology, cardiology, endocrinology, pharmacotherapy, and health promotion and disease prevention.
This book offers an authoritative and comprehensive overview of Lipoprotein(a). It provides an in-depth review of all aspects of Lp(a), from pathophysiology to metabolism. Chapters offer the reader a contemporary view of the important roles of Lp(a) as a risk factor for cardiovascular disease. In addition, this volume discusses the clinical implications of elevated Lp(a) and current and future therapies.
Lipoprotein(a) is an essential resource for physicians, medical students, residents, fellows, and allied health professionals in lipidology, cardiology, endocrinology, pharmacotherapy, and health promotion and disease prevention.
Caracteristici
Provides comprehensive coverage of lipoprotein(a) and its role in the development of cardiovascular disease Highlights current and future therapies for combating high levels of lipoprotein(a) Brings awareness to an often overlooked risk factor of heart attacks and other serious cardiovascular events