Local antimicrobial therapy in periodontitis involves direct placement of an antimicrobial agent(s) into subgingival sites. Use of the chlorhexidine chip (CHX) in conjunction with phase I periodontal therapy has shown some effectiveness in reducing periodontal probing depth, clinical attachment loss and bleeding on probing. Patients with chronic periodontitis having periodontal pocket depth ≥ 5 mm with age group 25-60 belonging to both sexes were included in the present study. The test site and the control site were randomly assigned. Along with phase I periodontal therapy, test sites received CHX chip while control site received placebo chip. Plaque index (PI), gingival index (GI), probing pocket depth (PPD), clinical attachment level (CAL) & gingival margin position (GP) were assessed at all selected sites at baseline and subsequently at 1,3, 6 and 9 months following the day of CHX chip & placebo chip placement. Radiographs were taken at baseline, 6 and 9 months. The results of the present study favours the use of chlorhexidine gluconate chip as an adjunct to phase I periodontal therapy in treatment of chronic periodontitis.