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Mechanisms of Morphogenesis

Autor Jamie A. Davies
en Limba Engleză Hardback – 18 apr 2013
Morphogenesis is the set of processes that generate shape and form in the embryo--an important area within developmental biology. An exciting and up-to-the-minute account of the very latest research into the factors that create biological form, Mechanisms of Morphogenesis, second edition is a text reference on the mechanisms of cell and tissue morphogenesis in a diverse array of organisms, including prokaryotes, animals, plants and fungi.
By combining hard data with computer modeling, Mechanisms of Morphogenesis, second edition equips readers with a much broader understanding of the scope of modern research than is otherwise available. The book focuses on the ways in which the genetic program is translated to generate cell shape, to direct cell migration, and to produce the shape, form and rates of growth of the various tissues. Each topic is illustrated with experimental data from real systems, with particular reference to gaps in current knowledge and pointers to future


  • Includes over 200 four-color figures
  • Offers an integrated view of theoretical developmental biology and computer modelling with laboratory-based discoveries
  • Covers experimental techniques as a guide to the reader
  • Organized around principles and mechanisms, using them to integrate discoveries from a range of organisms and systems
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Specificații

ISBN-13: 9780123910622
ISBN-10: 0123910625
Pagini: 414
Ilustrații: Illustrations
Dimensiuni: 191 x 235 x 25 mm
Greutate: 1.04 kg
Ediția:Revised
Editura: ELSEVIER SCIENCE

Public țintă

Cell and developmental biologists, research scientists, graduate and post-graduate students interested in developmental biology.

Cuprins

1) Introductory Section1.1 General introduction1.2 Key principles of morphogenesis1.3 The power and limitations of self-assembly2) Cell shape and the cell morphogenesis2.1 Morphogenesis by changing cell shape: a brief overview2.2 Shape in animal cells: tensegrity2.3 Making cellular processes2.4 Shape in plant cells3) Cell Migration3.1 Cell migration in development: a brief overview3.2 The nanomachinery of locomotion3.3 Guidance by chemotaxis3.4 Guidance by galvanotaxis3.5 Guidance by contact3.6 Waypoint navigation in the embryo3.7 Condensation of cells4) Epithelial Morphogenesis4.1 The epithelial state – brief overview4.2 Neighbour exchange and convergent extension4.3 Closure of holes4.4 Invagination and evagination4.5 Epithelial fusion4.6 Epithelial Branching5) Morphogenesis by cell proliferation and death 5.1 Growth, proliferation and death – a brief introduction5.2 Morphogenesis by orientated cell division5.3 Morphogenesis by elective cell death6) Conclusion and perspectives

Recenzii

"Davies retains from the first edition the concentration on morphogenesis itself…with other aspects of development taken for granted, and the organization that progresses in size from the sub-cellular systems critical for larger scale morphogenesis to mechanisms that concern whole population of cells… to keep the textbook manageable, he has presented some material more succinctly, such as the morphogenesis of sub-cellular structures." --ProtoView.com, January 2014