Mechanosensitivity of the Heart: Mechanosensitivity in Cells and Tissues, cartea 3

Molecular Mechanisms of Mechanotransduction in Cardiac Cells.- Titin and Titin-Associated Proteins in Myocardial Stress-Sensing and Mechanical Dysfunction.- Mechanical Stretch-Induced Reorganization of the Cytoskeleton and the Small GTPase Rac-1 in Cardiac Fibroblasts.- Molecular Signaling Mechanisms of Myocardial Stretch: Implications for Heart Disease.- Mechanical Stress Induces Cardiomyocyte Hypertrophy Through Agonist-Independent Activation of Angiotensin II Type 1 Receptor.- Mechanically Induced Potentials and Currents of the Cardiac Cells in Healthy and Diseased Myocardium.- Mechanostransduction in Cardiac and Stem-Cell Derived Cardiac Cells.- Stretch-Activated Channels in the Heart: Contribution to Cardiac Performance.- Effects of Applied Stretch on Native and Recombinant Cardiac Na+ Currents.- Mechanosensitive Alterations of Action Potentials and Membrane Currents in Healthy and Diseased Cardiomyocytes: Cardiac Tissue and Isolated Cell.- The Role of Mechanosensitive Fibroblasts in the Heart: Evidence from Acutely Isolated Single Cells, Cultured Cells and from Intracellular Microelectrode Recordings on Multicellular Preparations from Healthy and Diseased Cardiac Tissue.- Scanning Ion Conductance Microscopy for Imaging and Mechanosensitive Activation of Selected Areas of Live Cells.- Mechano-Electric Feedback in the Whole Heart and a Computer Simulation Study.- The Contribution of MEF to Electrical Heterogeneity and Arrhythmogenesis.- Mechanical Modulation of a Reentrant Arrhythmia: The Atrial Flutter Case.- Early Hypertrophic Signals After Myocardial Stretch. Role of Reactive Oxygen Species and the Sodium/Hydrogen Exchanger.- Stretch-Induced Inotropy in Atrial and Ventricular Myocardium.- Effects of Wall Stress on the Dynamics of Ventricular Fibrillation: A Computer Simulation Study of Mechanoelectric Feedback.- Electromechanical Modelling of Cardiac Tissue.- Arteries as a Source of Myogenic Contractile Activity: Ionic Mechanisms.- Specific Mechanotransduction Signaling Involved in Myogenic Responses of the Cerebral Arteries.

This is the first series of books that considers the problem of cell mechanosensitivity of organs and tissues at the molecular, biological, bio-physical, physiological and pharmacological levels and draws the attention to the global problem of the mechanosensitivity and its mechanisms In addition, the problem of intracellular crosstalk (i.e. a network of mechanically induced intracellular signaling cascades) is discussed for the first time