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Membrane Defenses Against Attack by Complement and Perforins de Charles J. Parker

Membrane Defenses Against Attack by Complement and Perforins: Current Topics in Microbiology and Immunology, cartea 178

Editat de Charles J. Parker
en Limba Engleză Paperback – 16 dec 2011
In this volume a comprehensive review of membrane proteinsthat regulate complement and perforin-mediated cytolysis ispresented. A detailed analysisis provided of thebiochemical, molecular, and functional features of theseproteins; the glycosyl phosphatidylinositol linkedproteins are covered, with emphasis placed on the functionalimportance of this type of membrane anchor. Further chaptersinclude reviews of the effects of complement activation oncells that are metabolically active, and of the regulationof cell killing by cytotoxic lymphocytes, considering thesimilarities and disparities between the complement andperforin systems. The therapeutic use of recombinant CR1for immune-mediated pathophysiological processes isdiscussed in a separate section.
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Specificații

ISBN-13: 9783642770166
ISBN-10: 3642770169
Pagini: 204
Ilustrații: VIII, 188 p. 5 illus.
Dimensiuni: 155 x 235 x 11 mm
Greutate: 0.29 kg
Ediția:Softcover reprint of the original 1st ed. 1992
Editura: Springer Berlin, Heidelberg
Colecția Springer
Seria Current Topics in Microbiology and Immunology

Locul publicării:Berlin, Heidelberg, Germany

Public țintă

Research

Cuprins

List of Contents.- Regulation of Complement by Membrane Proteins: An Overview.- Decay Accelerating Factor (CD55).- Complement Receptor Type 1.- Membrane Cofactor Protein.- Membrane Inhibitor of Reactive Lysis.- Homologous Restriction Factor.- The Effects of Complement Activation on Platelets.- Effects of the Membrane Attack Complex of Complement on Nucleated Cells.- Glycosyl-Phosphatidylinositol Anchoring of Membrane Proteins.- Paroxysmal Nocturnal Hemoglobinuria.- Perforin-Structure, Function, and Regulation.