Mental and Behavioral Dysfunction in Movement Disorders

1 Historical Issues in the Study of Behavioral Dysfunction in Movement Disorders.- 2 Fundamental and Clinical Evidence for Basal Ganglia Influences on Cognition.- 3 Integrating Cognition and Motivation into the Basal Ganglia Pathways of Action.- 4 Understanding Corticobasal Ganglia Networks as Part of a Habit Formation System.- 5 The Role of the Cerebellum in Cognition and Emotion.- 6 Assessing Cognition in Movement Disorders.- 7 Disorders of Intention in Parkinsonian Syndromes.- 8 Cognitive Control in Frontostriatal Disorders.- 9 Disorders of Speech and Language in Parkinson’s Disease.- 10 Distinctive Features of Apraxia in Corticobasal Degeneration and Other Neurological Illnesses.- 11 Neuropsychological Deficits in Cerebellar Syndromes.- 12 Induction and Reversal of Cognitive Deficits in a Primate Model of Huntington’s Disease.- 13 Induction and Reversal of Cognitive Deficits in a Primate Model of Parkinson’s Disease.- 14 Catecholamines and Cognition: Bridging the Gap Between Animal Studies and Clinical Syndromes.- 15 Nondopaminergic Influences on Cognition in Parkinson’s Disease.- 16 Cognitive Consequences of Neurosurgery for Parkinson’s Disease.- 17 The Clinical Spectrum of Dementia in Movement Disorders: An Overview.- 18 Neuropathological Distinctions and Similarities in Movement Disorders with Dementia.- 19 Homologies Between the Genetic Etiology and Pathogenesis of the Synucleinopathies and Tauopathies.- 20 Prevalence, Incidence, and Risk Factors for Dementia in Parkinson’s Disease.- 21 Neuropsychiatric Co-Morbidity in Dementia With and Without Movement Disorders.- 22 Neurotransmitter Correlates of Neuropsychiatric Symptoms in Dementia with Lewy Bodies.- 23 Acetylcholinesterase Inhibitors in the Treatment of Dementia in Parkinson’s Disease.- 24Mood Disorders and the Globus Pallidus.- 25 Cortical-Limbic-Striatal Dysfunction in Depression: Converging Findings in Basal Ganglia Diseases and Primary Affective Disorders.- 26 Agitation and Apathy in Hyper- and Hypokinetic Movement Disorders.- 27 Diagnosis and Treatment of Depression in Parkinson’s Disease.- 28 Diagnosis and Treatment of Hallucinations and Delusions in Parkinson’s Disease.- 29 REM Sleep Behavior Disorder in Parkinson’s Disease, Dementia with Lewy Bodies, and Multiple System Atrophy.- 30 Psychogenic Parkinsonism and Dystonia.- 31 Clinical Management of Psychosis and Mood Disorders in Huntington’s Disease.- 32 Clinical Management of Aggression and Frontal Symptoms in Huntington’s Disease.- 33 Heterogeneous Psychopathology of Tourette Syndrome.- 34 In Search of the Pathophysiology of Tourette Syndrome.- 35 Obsessive—Compulsive Disorder as a Frontostriatal-Thalamic Dysfunction.- 36 Dyskinesia in Patients with Schizophrenia Never Treated with Antipsychotics: Conceptual and Pathophysiological Implications.- 37 Medical and Psychosocial Determinants of Quality of Life in Parkinson’s Disease.- 38 Sexuality and Parkinson’s Disease.- 39 Daytime Sleepiness and Sleep Attacks in Idiopathic Parkinson’s Disease.- 40 Natural Evolution and Life Expectancy in Parkinson’s Disease.

"An impressive, diverse range of basic science and clinical topics are covered, at least some of which are certain to appeal to every reader...this book has much to offer researchers in this subject." -The Lancet

In addition to movement per se, movement disorders affect multiple mental processes and complex behavioral functions, and so must be taken into careful account when clinically managing a wide variety of behavioral problems. In Mental and Behavioral Dysfunction in Movement Disorders, internationally renowned researchers and clinicians review the many recent developments in the field, both to shed light on and to establish new standards for the study and treatment of the multiple cognitive, affective, and behavioral dysfunctions associated with movement disorders. These dysfunctions include depression, dementia, psychosis, sleep disorders arising from Parkinson's and Huntington's diseases, and Tourette syndrome, as well as multiple system atrophy, progressive supranuclear palsy, corticobasal degeneration, and many other related disorders. The authors describe these behavioral syndromes and their neurophysiological and neuropathological substratum, as well as their diagnostic criteria and therapeutic guidelines. For each syndrome, the cognitive deficits of attention, memory, language, praxis, and executive functions are spelled out in detail. Also discussed are the neuropsychiatry of movement disorders and the quality of life issues associated with Parkinson's disease.
Exhaustive and cutting-edge, Mental and Behavioral Dysfunction in Movement Disorders illuminates the many complex mental and behavioral conditions associated with these disorders, and constitutes an essential guide for all physicians treating these problems or scientists studying these topics today.

Includes supplementary material: sn.pub/extras