Microbial Communication: Mathematical Modeling, Synthetic Biology and the Role of Noise
Autor Sarangam Majumdar, Sisir Royen Limba Engleză Paperback – 17 sep 2021
The book further describes the phenomenon of noise, and discusses how noise plays a crucial role in gene expression and the quorum sensing circuit operationusing a set of tools like frequency domain analysis, power spectral density, stochastic simulation and the whitening effect. It also explores various aspects of synthetic biology (related to bacterial communication), such as genetic toggle switch, bistable gene regulatory networks, transcriptional repressor systems, pattern formation, syntheticcooperation, predator-prey synthetic systems, dynamical quorum sensing, synchronized quorum of genetic clocks, role of noise in synthetic biology, the Turing test and stochastic Turing test.
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Specificații
ISBN-13: 9789811574191
ISBN-10: 9811574197
Pagini: 175
Ilustrații: XVII, 175 p. 35 illus., 18 illus. in color.
Dimensiuni: 155 x 235 mm
Ediția:1st ed. 2020
Editura: Springer Nature Singapore
Colecția Springer
Locul publicării:Singapore, Singapore
ISBN-10: 9811574197
Pagini: 175
Ilustrații: XVII, 175 p. 35 illus., 18 illus. in color.
Dimensiuni: 155 x 235 mm
Ediția:1st ed. 2020
Editura: Springer Nature Singapore
Colecția Springer
Locul publicării:Singapore, Singapore
Cuprins
Chapter 1. Introduction.- Chapter 2. Talking about talking microbes.- Chapter 3. Mathematical models of quorum sensing molecular mechanisms.- Chapter 4. Mathematical models of quorum sensing regulated biofilms development.- Chapter 5. Mathematical models of bacterial swarming behaviour regulated by quorum sensing. Chapter 6. Mathematical models of bacterial quorum sensing regulated virulence factors.- Chapter 7. Evolutionary models of bacterial communication systems.- Chapter 8. Pattern formation in bacterial conversation mechanisms.- Chapter 9. Summary of Experimental Results.- Chapter 10. Therapy related mathematical models and quorum quenching.- Chapter 11. Role of noise in microbial communication.- Chapter 12. Electrical communication systems in bacterial biofilms and ion-channels.- Chapter 13. Synthetic biology and microbial communication.- Chapter 14. Role of Noise in Synthetic Biology.-Chapter 15 Noise in Science and Technology Vs Biological System.
Notă biografică
Sarangam Majumdar is a mathematician. He holds a Bachelor of Science and Master of Science in Mathematics from the University of Calcutta (2010) and National Institute of Technology, Rourkela (2012), respectively. He has worked with Prof. Sisir Roy, Indian Statistical Institute, Kolkata; Prof. Rodolfo Llinas, New York University School of Medicine, USA; Prof. Dr. Suman Datta, University of Calcutta; Prof. S. Chakraverty, National Institute of Technology, Rourkela; Dr. Sukla Pal, University of Otago,NewZeland; Prof. Rodolfo Repetto, Dipartimento di Ingegneriadelle Costruzioni, dell'Ambiente e del Territorio, Università degl iStudi di Genova, Italy; Prof. Nicola Guglielmi, Università degli Studi di L' Aquila and many more. His research interests include mathematical biology, system biology, mathematical modeling, numerical analysis, scientific computing, nonlinear dynamics and chaos, and over the past eight yearshe has focused on bacterial communication systems (quorum sensing, electrical communication). He has published several papers in various peer-reviewed, international journals and book chapters (in Springer). He is also a reviewer for a number of international journals.
Textul de pe ultima copertă
This book introduces the concept of bacterial communication systems from a mathematical modeling point of view. It sheds light on the research undertaken in the last three decades, and the mathematical models that have been proposed to understand the underlying mechanism of such systems. These communication systems are related to quorum sensing mechanisms and quorum sensing regulated processes such as biofilm formation, gene expression, bioluminescence, swarming and virulence.
The book further describes the phenomenon of noise, and discusses how noise plays a crucial role in gene expression and the quorum sensing circuit operationusing a set of tools like frequency domain analysis, power spectral density, stochastic simulation and the whitening effect. It also explores various aspects of synthetic biology (related to bacterial communication), such as genetic toggle switch, bistable gene regulatory networks, transcriptional repressor systems, pattern formation,synthetic cooperation, predator-prey synthetic systems, dynamical quorum sensing, synchronized quorum of genetic clocks, role of noise in synthetic biology, the Turing test and stochastic Turing test.
Caracteristici
Elaborates on all the different kinds of microbial communication systems Describes the role of noise in the context of microbial communication Provides insights into the mathematical models, experimental observations, synthetic biology and the relevance of quantum theory in understanding microbial communication