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Mitochondrial Function In Vivo Evaluated by NADH Fluorescence

Autor Avraham Mayevsky
en Limba Engleză Paperback – 14 oct 2016
This book covers both the technological development and biomedical applications of NADH fluorescence. Topics covered include perspectives on the history of monitoring NADH fluorescence, the relationship between mitochondrial function and other functions at the tissue level, responses of NADH to physiological and pathophysiological conditions, monitoring of NADH in the human brain and other organs, and metabolism. It also includes an in-depth look at flavoprotein (Fp) fluorescence and NADH in relation to redox state. This is an ideal book for biomedical engineers, researchers, and graduate students interested in learning the biomedical applications of NADH fluorescence.
This book also:
  • Covers multisite monitoring of NADH, as well as multiparametric responses of NADH to physiological and pathophysiological conditions, and monitoring of various organs in various animal models
  • Describes the relationship between brain activation (i.e. epileptic activity and cortical spreading depression) and NADH redox state
  • Presents the effects of hypoxia,hyperbaric hyperoxia, and ischemia on brain NADH fluorescence and other tissue physiological parameters
 
About the Author
Avraham Mayevsky, Ph.D. is a Professor Emeritus in theFaculty of Life Sciences and the Brain Research Center at Bar Ilan University, Israel.
He has published  more than two hundred papers in the field of mitochondrial function and tissue physiology in vivo under pathophysiological conditions.
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Specificații

ISBN-13: 9783319355832
ISBN-10: 331935583X
Pagini: 290
Ilustrații: XIV, 276 p. 234 illus., 63 illus. in color.
Dimensiuni: 210 x 279 mm
Greutate: 0 kg
Ediția:Softcover reprint of the original 1st ed. 2015
Editura: Springer International Publishing
Colecția Springer
Locul publicării:Cham, Switzerland

Cuprins

1. Introduction.- 2. Tissue Energy Metabolism and Mitochondrial Function.- 3. Spectroscopic monitoring of NADH – Historical Overview.- 4. Technological aspects of NADH monitoring In Vivo.- 5. Monitoring of NADH together with other tissue physiological parameters.- 6. Multisite Monitoring of NADH.- 7. Responses of NADH to physiological and pathophysiological conditions.- 8. Monitoring of various organs in various animal models.- 9. Monitoring of NADH in Human brain and body organs.- 10. Discussion.- Index.

Recenzii

“This is a great book conctning t history,physiology of multiple organs responses to normoxia, hypoxia, ischemic,hyperoxia, & hyperbaric conditions in anesthetized, awake, mammalsincluding humans. … I recommend this book for historians of Physiology,researchers in Neurology, neurosurgeons and students of Physiology.” (Joseph J.Grenier, Amazon.com, November, 2015)

Notă biografică

About the Author
Avraham Mayevsky, Ph.D. is a Professor Emeritus in theFaculty of Life Sciences and the Brain Research Center at Bar Ilan University, Israel.
He has published  more than two hundred papers in the field of mitochondrial function and tissue physiology in vivo under pathophysiological conditions.

Textul de pe ultima copertă

This book covers both the technological development and biomedical applications of NADH fluorescence. Topics covered include perspectives on the history of monitoring NADH fluorescence, the relationship between mitochondrial function and other functions at the tissue level, responses of NADH to physiological and pathophysiological conditions, monitoring of NADH in the human brain and other organs, and metabolism. It also includes an in-depth look at flavoprotein (Fp) fluorescence and NADH in relation to redox state. This is an ideal book for biomedical engineers, researchers, and graduate students interested in learning the biomedical applications of NADH fluorescence.
This book also:
  • Covers multisite monitoring of NADH, as well as multiparametric responses of NADH to physiological and pathophysiological conditions, and monitoring of various organs in various animal models
  • Describes the relationship between brain activation (i.e. epileptic activity and cortical spreading depression) and NADH redox state
  • Presents the effects of hypoxia, hyperbaric hyperoxia, and ischemia on brain NADH fluorescence and other tissue physiological parameters
  
About the Author
Avraham Mayevsky, Ph.D. is a Professor Emeritus in the Faculty of Life Sciences and the Brain Research Center at Bar Ilan University, Israel.
He has published  more than two hundred papers in the field of mitochondrial function and tissue physiology in vivo under pathophysiological conditions.

Caracteristici

Describes the subject matter in detail citing most of the 700 published papers in this field
Presents the relationship between mitochondrial function and other functions at the tissue level
Presents optical monitoring at the human level