Mitochondrial Oxidative Phosphorylation: Nuclear-Encoded Genes, Enzyme Regulation, and Pathophysiology
Editat de Bernhard Kadenbachen Limba Engleză Paperback – 18 iul 2014
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Specificații
ISBN-13: 9781493901562
ISBN-10: 1493901567
Pagini: 384
Ilustrații: XII, 372 p.
Dimensiuni: 155 x 235 x 20 mm
Greutate: 0.54 kg
Ediția:2012
Editura: Springer
Colecția Springer
Locul publicării:New York, NY, United States
ISBN-10: 1493901567
Pagini: 384
Ilustrații: XII, 372 p.
Dimensiuni: 155 x 235 x 20 mm
Greutate: 0.54 kg
Ediția:2012
Editura: Springer
Colecția Springer
Locul publicării:New York, NY, United States
Public țintă
ResearchCuprins
Preface.- Introduction.- Mitochondrial Dynamics: The Intersection of Form and Function.- Biogenesis of Mitochondrial Proteins.- Assembly Factors of Human Mitochondrial Respiratory Chain Complexes: Physiology and Pathophysiology.- Supramolecular Organization of the Mitochondrial Respiratory Chain: A New Challenge for the Mechanism and Control of Oxidative Phosphorylation.- Molecular Mechanisms of Superoxide Production by the Mitochondrial Respiratory Chain.- Studies on the Function and Regulation of Mitochondrial Uncoupling Proteins.- Evolution of the Couple Cytochrome C and Cytochrome C Oxidase in Primates.- Reaction Mechanism of Mammalian Mitochondrial Cytochrome C Oxidase.- Phosphorylation of Mammalian Cytochrome C and Cytochrome C Oxidase in the Regulation of Cell Destiny: Respiration, Apoptosis, and Human Disease.- Individual Biochemical Behavior Versus Biological Robustness: Spotlight on the Regulation of Cytochrome C Oxidase.- Bigenomic Regulation of Cytochrome C Oxidase in Neurons and the Tight Coupling Between Neuronal Activity and Energy Metabolism.- Cytochrome C Oxidase and its Role in Neurodegeneration and Neuroprotection.- The Many Clinical Faces of Cytochrome C Oxidase Deficiency.- Index.
Caracteristici
Describes the nuclear encoded genes and their expressed proteins of mitochondrial oxidative phosphorylation New approaches to study mitochondrial genetics, function, and disease Examines the structure and function of complex I and complex III Includes supplementary material: sn.pub/extras