Molecular Basis of Pancreas Development and Function: Endocrine Updates, cartea 11
Editat de Joel F. Habener, Mehboob Hussainen Limba Engleză Hardback – 31 ian 2001
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Specificații
ISBN-13: 9780792372714
ISBN-10: 0792372719
Pagini: 412
Ilustrații: XIV, 412 p.
Dimensiuni: 155 x 235 x 30 mm
Greutate: 0.84 kg
Ediția:2001
Editura: Springer Us
Colecția Springer
Seria Endocrine Updates
Locul publicării:New York, NY, United States
ISBN-10: 0792372719
Pagini: 412
Ilustrații: XIV, 412 p.
Dimensiuni: 155 x 235 x 30 mm
Greutate: 0.84 kg
Ediția:2001
Editura: Springer Us
Colecția Springer
Seria Endocrine Updates
Locul publicării:New York, NY, United States
Public țintă
ResearchCuprins
1. An Historical and Phylogenetic Perspective of Islet-Cell Development.- 2. Glucose Signalling to Transcription Factors of the Insulin Gene.- 3. ?-Cell Dysfunction and Chronic Hyperglycaemia.- 4. Glucose Toxicity of the Pancreatic ?-cell.- 5. The ?-Cell and Regulation of Glucagon Gene Transcription.- 6. The KATP Channel and the Sulfonylurea Receptor.- 7. Glucagon-Like Peptide-1: An Insulinotropic Hormone with Potent Growth Factor Actions at the Pancreatic Islets of Langerhan.- 8. Communication of Islet Cells: Molecules and Functions.- 9. Soluble Factors Important for Pancreas Development.- 10. Role of Mesenchymal-Epithelial Interactions in Pancreas Development.- 11. Homeodomain Proteins in Pancreas Development.- 12. bHLH Factors and Notch in Pancreatic Development.- 13. Identification, Biological Functions, and Contribution to Human Diabetes of Islet-Brain 1.- 14. Pax4 and Pax6 in Islet Differentiation.- 15. The Role of the Hepatocyte Nuclear Factor Network in Glucose Homeostasis.- 16. Regulation of PDX-1 Gene Expression.- 17. Mechanisms of Postnatal ?-Cell Mass Regulation.- 18. Genetic Models of Insulin Resistance: Alterations in ?-Cell Biology.- 19. Clinical Consequences of Genetic Defects in ?-Cell Genes.- 20. Pathophysiology of Glut2 in Diabetes Mellitus.- 21. Use of a Cre-LoxP Strategy in Mice to Determine the Cell-Specific Roles of Glucokinase in MODY-2.- 22. Development of ?-Cell Lines for Transplantation in Type 1 Diabetes Mellitus.- 23. Gene Therapeutic Approaches for ?-Cell Replacement.- Colour Figures.
Recenzii
`A very interesting text for both research and clinical endocrinologists.'
Journal of Pediatric Endocrinology and Metabolism, 15:4 (2002)
Journal of Pediatric Endocrinology and Metabolism, 15:4 (2002)