Molecular Biology of Brain and Endocrine Peptidergic Systems: Biochemical Endocrinology
Editat de M. Chretienen Limba Engleză Paperback – 3 ian 2013
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Specificații
ISBN-13: 9781468488036
ISBN-10: 1468488031
Pagini: 336
Ilustrații: XI, 321 p.
Dimensiuni: 178 x 254 x 18 mm
Greutate: 0.59 kg
Ediția:Softcover reprint of the original 1st ed. 1988
Editura: Springer Us
Colecția Springer
Seria Biochemical Endocrinology
Locul publicării:New York, NY, United States
ISBN-10: 1468488031
Pagini: 336
Ilustrații: XI, 321 p.
Dimensiuni: 178 x 254 x 18 mm
Greutate: 0.59 kg
Ediția:Softcover reprint of the original 1st ed. 1988
Editura: Springer Us
Colecția Springer
Seria Biochemical Endocrinology
Locul publicării:New York, NY, United States
Public țintă
ResearchCuprins
Genetic Engineering of Polypeptide Hormones (Mutagenesis).- Functional Dissection of a cAMP-Response Element Using Recombinant Mutations.- Structure Activity Relationship and Peptide Drug Design.- Conformational Constraints in the Design of Receptor Selective Peptides: Conformational Analysis and Molecular Dynamics.- Angiotensin II Antagonists with Prolonged Duration of Action, Possible Anti-Hypertensive Drugs.- New Concepts in Peptide Analog Design.- Clinical and Experimental Applications of Polypeptide Hormones.- Neuropeptidergic Pathways as Possible Targets for the Development of New Therapeutic Agents.- Combination Therapy with the Antiandrogen Flutamide and the LHRH Agonist [D-Trp6, des-Gly-NH210]LHRH Ethylamide in Prostate Cancer: Rationale and 5-year Clinical Experience.- Organelle Organization and Intracellular Trafficking.- Proinsulin Conversion Site.- Hormone and Receptor Ligand Interactions.- Regulation of the Adenylate Cyclase Signalling Pathway: Potential Role for the Phosphorylation of the Catalytic Unit by Protein Kinase A and Protein Kinase C.- Role of Glycosylation in Ligand-Receptor Interactions and Signal Transduction Mechanisms.- Post-Translational Processing of Peptide Hormones.- Molecular Structure of Neutral Endopeptidase 24.11 (Enkephalinase).- The Possible Role of Plasma Kallikrein in Pro-Hormone and Pro-Enzyme Processing.- Sequence Analysis of the Carboxypeptidase E Precursor.- Cellular Mechanisms of Peptide Processing: Focus on ?-Amidation.- The Yeast KEX1 Gene Product Acts as a Carboxypeptidase B-Like Protease in Processing Secreted Protein Precursors.- Receptor Localization and in Situ Hybridization.- Regulation of mRNA in Peptidergic Systems: Quantitative and In Situ Studies.- Cellular and Sub-Cellular Localization of Brain NeurotensinReceptors.- Gonadotropins and Novel Gonadal Peptides. Isolation, Structure and Cloning.- Diversity of Novel Proteins of Gonadal Fluids.- Biochemical and Biological Characterization of LH and FSH Expressed by Recombinant DNA Technology.- Regulation of Neuropeptide Gene Expression.- DNA Binding Proteins and Their Roles in Controlling Tissue Specific Gene Expression and the Responses to Second Messengers.- Molecular Biology and Physiology of Aplysia Neuropeptides.