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Muscular and Skeletal Anomalies in Human Trisomy in an Evo-Devo Context: Description of a T18 Cyclopic Fetus and Comparison Between Edwards (T18), Patau (T13) and Down (T21) Syndromes Using 3-D Imaging and Anatomical Illustrations

Autor Rui Diogo, Christopher M. Smith, Janine M. Ziermann, Julia Molnar, Marjorie C. Gondre-Lewis, Corinne Sandone, Edward T. Bersu, Mohammed Ashraf Aziz
en Limba Engleză Hardback – 25 feb 2015
This book focuses on human anatomy and medicine and specifically on both muscular and skeletal birth defects in humans with trisomy. Moreover, this book also deals with Down syndrome, which is one of the most studied human syndromes and, due to its high incidence and the fact that individuals with this syndrome often live until adulthood, is of special interest to the scientific and medical community.


This new line of inquiry is addressed to a wide audience, including medical researchers, physicians, surgeons, medical and dental students, pathologists, and pediatricians, among others, while also being of interest to developmental and evolutionary biologists, anatomists, functional morphologists, and zoologists.
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Specificații

ISBN-13: 9781498711371
ISBN-10: 1498711375
Pagini: 222
Ilustrații: 130 black & white illustrations, 25 colour illustrations
Dimensiuni: 178 x 254 x 18 mm
Greutate: 0.59 kg
Ediția:1
Editura: CRC Press
Colecția CRC Press

Public țintă

Professional Practice & Development

Cuprins

Topics and purpose of this book. The musculoskeletal system of a 28-week human Trisomy 18 cyclopia fetus. Comparative anatomy of muscular anomalies of Trisomies 13, 18, and 21. Cyclopia, trisomic anomalies, and order versus chaos in development and evolution. Digits and muscles: topology-directed muscle attachment. Evolutionary theory and mouse models for Down syndrome. Appendix A - Dissection photographs of Trisomy 18 human cyclopia fetus. Appendix B - 3-D renders of Trisomy 18 human cyclopia fetus CT scan data. References. Index.

Notă biografică

Diogo, Rui; Smith, Christopher M.; Ziermann, Janine M.; Molnar, Julia; Gondre-Lewis, Marjorie C.; Sandone, Corinne; Bersu, Edward T.; Aziz, Mohammed Ashraf

Descriere

The first of its kind, this groundbreaking book utilizes data previously obtained to research the evolution of primates and applies it to humans. Completely unique in perspective, it analyzes the anatomy of the human body and its variations and defects and explores both their medical implications and their applications in an evolutionary-developmental (evo-devo) context. It specifically addresses both muscular and skeletal birth defects in human trisomy, and contains a detailed discussion of Down syndrome, one of the most studied human syndromes.