Neurodegenerative Diseases: Clinical Aspects, Molecular Genetics and Biomarkers
Editat de Daniela Galimberti, Elio Scarpinien Limba Engleză Paperback – 25 ian 2019
Neurodegenerative Diseases is aimed at clinicians, particularly those workingin academic hospitals. This multidisciplinary book will also be of interest to basic researchers in medical fields.
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Specificații
ISBN-13: 9783030102890
ISBN-10: 3030102890
Pagini: 407
Ilustrații: X, 407 p. 23 illus., 20 illus. in color.
Dimensiuni: 155 x 235 x 27 mm
Greutate: 0.68 kg
Ediția:Softcover reprint of the original 2nd ed. 2018
Editura: Springer International Publishing
Colecția Springer
Locul publicării:Cham, Switzerland
ISBN-10: 3030102890
Pagini: 407
Ilustrații: X, 407 p. 23 illus., 20 illus. in color.
Dimensiuni: 155 x 235 x 27 mm
Greutate: 0.68 kg
Ediția:Softcover reprint of the original 2nd ed. 2018
Editura: Springer International Publishing
Colecția Springer
Locul publicării:Cham, Switzerland
Cuprins
Role of Genetics and Epigenetics in neurodegenerative disorders of the central nervous system.- Diagnosis and treatment of Alzheimer’s Disease and atypical forms.- Autosomal Dominant Alzheimer’s Disease: Underlying Causes.- Genetic Risk Factors for sporadic Alzheimer’s Disease.- The Role of Cerebrovascular Disease in Cognitive Decline.- Environmental Risk Factors in Alzheimer’s Disease and Mild Cognitive Impairment.- Diagnosis of Frontotemporal dementia.- Autosomal dominant Frontotemporal Lobar Degeneration: from genotype to phenotype.- Genetic Risk Factors for sporadic Frontotemporal Dementia.- Alzheimer’s Disease and Frontotemporal Lobar Degeneration: Mouse Models.- Cerebrospinal Fluid Biomarkers in Alzheimer’s Disease and Frontotemporal Dementia.- Biomarkers for Alzheimer’s Disease and Frontotemporal Lobar Degeneration: Imaging.- Amyotrophic Lateral Sclerosis: Genotypes and Phenotypes.- Lewy Body dementia.- Rare Dementias.- Neurodevelopment Alterations, Neurodegeneration, and Immunoinflammatory Patterns in the Pathophysiology of Schizophrenia and bipolar disorders.- Parkinson’s disease.- Neurodegeneration and Multiple Sclerosis.
Notă biografică
Dr. Galimberti is the Secretary of the Dementia Panel of the European Academy of Neurology and the Italian Society for the research on dementia (Sindem).
She is author of more than 250 scientific articles in international peer-reviewed journals, 10 chapters in international volumes, and more than 350 contributions to conferences. She serves as reviewer for several neurological journals. She is a Senior Associate Editor of the “Journal of Alzheimer’s disease”.
Elio Scarpini got his degree in Neurology in 1981 and he is professor of Neurology at the University of Milan. He is the Chief of the Alzheimer Center at the Policlinico University Hospital (Milan, Italy). His main interests include clinical and therapeutic aspects of neurodegenerative disorders (Alzheimer’s disease, Frontotemporal Lobar Degeneration) and demyelinating diseases (Multiple Sclerosis).
He is author of more than 300 scientific articles in international peer-reviewed journals and serves as reviewerfor several neurological journals.
She is author of more than 250 scientific articles in international peer-reviewed journals, 10 chapters in international volumes, and more than 350 contributions to conferences. She serves as reviewer for several neurological journals. She is a Senior Associate Editor of the “Journal of Alzheimer’s disease”.
Elio Scarpini got his degree in Neurology in 1981 and he is professor of Neurology at the University of Milan. He is the Chief of the Alzheimer Center at the Policlinico University Hospital (Milan, Italy). His main interests include clinical and therapeutic aspects of neurodegenerative disorders (Alzheimer’s disease, Frontotemporal Lobar Degeneration) and demyelinating diseases (Multiple Sclerosis).
He is author of more than 300 scientific articles in international peer-reviewed journals and serves as reviewerfor several neurological journals.
Textul de pe ultima copertă
This book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer’s disease, frontotemporal lobar degeneration, Lewy body dementia,Parkinson’s disease, amyotrophic lateral sclerosis, and additional less common neurodegenerative diseases. Both clinical and basic aspects of each disease are treated, including novel diagnostic criteria, old and new treatments, basic discoveries (genetics, epigenetics and molecular biology), and translation of basic research into biomarkers for early diagnosis, particularly to identify peripheral biomarkers. In addition, emerging data indicate that neurodegeneration seems to also be present in classically non-degenerative disorders. Therefore, a chapter about overlapping mechanisms between dementias and psychiatric disorders is included, as well as a description of the role of neurodegeneration in multiple sclerosis.
Neurodegenerative Diseases is aimed at clinicians, particularly those workingin academic hospitals. This multidisciplinary book will also be of interest to basic researchers in medical fields.
Neurodegenerative Diseases is aimed at clinicians, particularly those workingin academic hospitals. This multidisciplinary book will also be of interest to basic researchers in medical fields.
Caracteristici
Includes four new chapters on recent developments Translational (from bench to bedside) approach Covers neurodegeneration in classically non-degenerative disorders
Recenzii
From the reviews:
“This monograph on neurodenerative diseases and animal models covers a broad spectrum of molecular biology, biomarkers, and in depth descriptions concerning Alzheimers Disease, both genetic and nongenetic. The book is of importance to neurology researchers, students, and biochemists with a research interest in Alzheimer’s Disease.” (Joseph J. Grenier, Amazon.com, May, 2014)
“This monograph on neurodenerative diseases and animal models covers a broad spectrum of molecular biology, biomarkers, and in depth descriptions concerning Alzheimers Disease, both genetic and nongenetic. The book is of importance to neurology researchers, students, and biochemists with a research interest in Alzheimer’s Disease.” (Joseph J. Grenier, Amazon.com, May, 2014)