“Neutrinos and Explosive Events in the Universe” brought together experts from diverse disciplines to offer a detailed view of the exciting new work in this part of High Energy Astrophysics. Sponsored by NATO as an Advanced Study Institute, and coordinated under the auspices of the International School of Cosmic Ray Astrophysics (14th biennial course), the ASI featured a full program of lectures and discussion in the ambiance of the Ettore Majorana Centre in Erice, Italy, including visits to the local Dirac and Chalonge museum collections as well as a view of the cultural heritage of southern Sicily. Enri- ment presentations on results from the Spitzer Infrared Space Telescope and the Origin of Complexity complemented the program. This course was the best attended in the almost 30 year history of the School with 121 participants from 22 countries. The program provided a rich ex- rience, both introductory and advanced, to fascinating areas of observational Astrophysics Neutrino Astronomy, High Energy Gamma Ray Astronomy, P- ticle Astrophysics and the objects most likely responsible for the signals - plosions and related phenomena, ranging from Supernovae to Black Holes to the Big Bang. Contained in this NATO Science Series volume is a summative formulation of the physics and astrophysics of this newly emerging research area that already has been, and will continue to be, an important contributor to understanding our high energy universe.