Non-Neuronal Mechanisms of Brain Damage and Repair After Stroke de Jun Chen

Non-Neuronal Mechanisms of Brain Damage and Repair After Stroke: Springer Series in Translational Stroke Research

Jun Chen

John H. Zhang

Xiaoming Hu

This book provides a comprehensive overview of the latest research in the role of non-neuronal cells - astrocytes, oligodendrocytes, endothelial cells, pericytes, microglia, and other immune cells in ischemic brain injury and long-term recovery. In these cases, neurodegeneration and brain repair are controlled in a sophisticated system, incorporating interactions between different cell types and cellular systems. Also explored are the therapeutic strategies that target non-neuronal responses after stroke and their translational potentials.

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	Preț	Express
Paperback (1)	914^.50 lei 6-8 săpt.
Springer International Publishing – 12 iun 2018	914^.50 lei 6-8 săpt.
Hardback (1)	920^.43 lei 6-8 săpt.
Springer International Publishing – 19 aug 2016	920^.43 lei 6-8 săpt.

Preț

Express

Paperback (1)

914^.50 lei 6-8 săpt.

Springer International Publishing – 12 iun 2018

914^.50 lei 6-8 săpt.

Hardback (1)

920^.43 lei 6-8 săpt.

Springer International Publishing – 19 aug 2016

920^.43 lei 6-8 săpt.

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Specificații

ISBN-13: 9783319323350
ISBN-10: 3319323350
Pagini: 466
Ilustrații: XIII, 408 p. 49 illus., 44 illus. in color.
Dimensiuni: 155 x 235 x 24 mm
Greutate: 0.77 kg
Ediția:1st ed. 2016
Editura: Springer International Publishing
Colecția Springer
Seria Springer Series in Translational Stroke Research

Locul publicării:Cham, Switzerland

Cuprins

Part 1. Microvascular integrity in stroke.- 1. Structural alterations to the endothelial tight junction complex during stroke.- 2. Role of pericytes in neurovascular unite and stroke.- 3. Glial support of blood-brain barrier integrity: Molecular targets for novel therapeutic strategies in stroke.- 4. Barrier mechanism in neonatal stroke.- 5. Angiogenesis: a realistic therapy for ischemic stroke.- Part 2. Glial cells in stroke.- 6. Astrocytes as a target for ischemic stroke.- 7. Microglia: a double-sided sword in stroke.- 8. Crosstalk between cerebral endothelium and oligodendrocyte after stroke.- Part 3. Peripheral immune cells in stroke.- 9. The peripheral immune response to stroke.- 10. The Role of spleen-derived immune cells in ischemic brain injury.- 11. Regulatory T cells in ischemic brain injury.- 12. B cells in stroke and preconditioning-induced protection against stroke.- 13. Mast cell as an early responder in ischemic brain injury.- 14. Roles of neutrophils in stroke.- 15. Thefunction of cytokines in ischemic stroke.- Part 4. White matter injury and repair in stroke.- 16. Ischemic injury to white matter: an age-dependent process.- 17. Neurovascular repair after stroke.- 18. The role of non-neuronal Nrf2 pathway in ischemic stroke: damage control and potential tissue repair.- 19. Stem cell therapy for ischemic stroke.

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Caracteristici

Discusses the roles of astrocytes, microglia, oligodendrocytes, endothelial cells, pericytes, and other immune cells Explores which therapies hold promise for translation to humans Only comprehensive overview of non-neuronal cells in ischemic stroke and recovery Includes supplementary material: sn.pub/extras