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Novartis Foundation Symposium 288 – Cortical Development – Genes and Genetic Abnormalities de Novartis

Novartis Foundation Symposium 288 – Cortical Development – Genes and Genetic Abnormalities: Novartis Foundation Symposia

Autor Novartis
en Limba Engleză Hardback – 24 ian 2008
The billions of cells in the human brain and the trillions of connections between them are the result of the complex interactions between our unfolding genetic programme and our environment. While our genome is the blueprint for development, it is the combination of genetic susceptibility and environmental perturbations that can lead to several devastating diseases including neural tube closure defects, schizophrenia, autism and attention deficit disorder.

To understand the brain and its diseases, we therefore need to reveal the mechanisms by which the brain develops and the ways in which it can constantly change throughout a lifetime.

The gap between basic research into brain development and understanding of clinical disorders is now finally shrinking. This book provides a unique and timely view of this crossover, featuring in-depth discussion between leading developmental neurobiologists and clinicians involved in the management of patients with disorders of the nervous system. Chapters deal specifically with:

  • cell fate determination
  • cell migration and disorders of cell migration
  • current concepts and new ideas about cortical arealisation, and disorders which can arise from incorrect arealisation
  • genes implicated in the development of cortical connectivity and related pathologies such as schizophrenia and synaesthesia
  • and susceptibility genes for cognitive disorders such as schizophrenia, autism, dyslexia, and attention deficit disorder

Cortical Development: Genes and Genetic Abnormalities contains contributions from researchers and clinicians working in the fields of molecular and cell biology, developmental neurobiology, neurology, neuropathology and psychiatry and thus offers an integrated approach to the problems of cortical development disorders.

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Specificații

ISBN-13: 9780470060926
ISBN-10: 0470060921
Pagini: 302
Dimensiuni: 162 x 239 x 19 mm
Greutate: 0.6 kg
Ediția:No. 288
Editura: Wiley
Seria Novartis Foundation Symposia

Locul publicării:Chichester, United Kingdom

Public țintă

Primary: Developmental neurobiologists, developmental biologists Secondary:  Cell and molecular biologists, neuroscientists, neuroanatomists, neurologists, psychiatrists

Notă biografică

The Novartis Foundation is an international scientific and educational charity which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research.

Chair: John Parnavelas, University College London, UK.

Descriere

To understand the brain and its devastating diseases, we need to reveal the mechanisms that produce it and the ways in which it can constantly change throughout a lifetime. This book features a timely and insightful discussion between developmental neurobiologists and clinicians who deal with disorders of the nervous system.