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Nutrigenomics

Autor Carsten Carlberg, Stine Marie Ulven, Ferdinand Molnár
en Limba Engleză Hardback – 21 iun 2016
The fascinating area of Nutrigenomics describes this daily communication between diet, food and nutrients, their metabolites and our genome. This book describes how nutrition shapes human evolution and demonstrates its consequences for our susceptibility to diseases, such as diabetes and atherosclerosis. Inappropriate diet can yield stress for our cells, tissues and organs and then it is often associated with low-grade chronic inflammation. Overnutrition paired with physical inactivity leads to overweight and obesity and results in increased burden for a body that originally was adapted for a life in the savannas of East Africa. Therefore, this textbook does not discuss a theoretical topic in science, but it talks about real life, and our life-long “chat” with diet. We are all food consumers, thus each of us is concerned by the topic of this book and should be aware of its mechanisms.   
The purpose of this book is to provide an overview on the principles of nutrigenomics and their relation to health or disease. We are not aiming to compete with more comprehensive textbooks on molecular nutrition, evolutionary biology, genomics, gene regulation or metabolic diseases, but rather will focus on the essentials and will combine, in a compact form, elements from different disciplines. In order to facilitate the latter, we favor a high figure-to-text ratio following the rule “a picture tells more than thousand words”.   
The content of this book is based on the lecture course “Nutrigenomics”, which is held since 2003 once per year by Prof. Carlberg at the University of Eastern Finland in Kuopio. The book is subdivided into three sections and twelve chapters. Following the "Introduction" there are sections on the "Molecular genetic basis" and the "Links to disease", which take a view on nutrigenomics from the perspective of molecular mechanisms or from the causes of metabolic diseases, respectively.     
Besidesits value as a textbook, Nutrigenomics will be a usefull reference for individuals working in biomedicine.         
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Specificații

ISBN-13: 9783319304137
ISBN-10: 3319304135
Pagini: 210
Ilustrații: XXI, 222 p. 103 illus., 101 illus. in color.
Dimensiuni: 155 x 235 x 19 mm
Greutate: 4.91 kg
Ediția:1st ed. 2016
Editura: Springer International Publishing
Colecția Springer
Locul publicării:Cham, Switzerland

Cuprins

Nutrition and common diseases.- Human genomic variation.- Sensing nutrition.- Nutrigenomics: Adapting the human genome to dietary changes and personalized nutrition.- Nutritional epigenomics.- Nutritional signaling and aging.- Chronic inflammation and metabolic stress.- Obesity.- Glucose homeostasis, insulin resistance and β cell failure.- Diabetes.- Hypertension, atherosclerosis and dyslipidemias.- Metabolic syndrome.  

Recenzii

               

Notă biografică

Prof. Carsten Carlberg: Professor for biochemistry at the School of Medicine, Institute of Biomedicine at the University of Eastern Finland. The main research interests of Prof. Carlberg are (epi)genomics of nuclear receptors and their ligands with special focus on vitamin D. So far he published more than 190 papers (H-index 50). Since 2003 he is lecturing yearly the course "Nutrigenomics", which is the basis of this textbook. Together with Dr. Molnár he also published the Springer textbook "Mechanisms of gene regulation".
Prof. Stine Marie Ulven: Professor at the Department of Nutrition, Institute of Basic Medical Sciences at the University of Oslo (Norway). The main research interests of Prof. Ulven are human dietary intervention studies and diet-gene interactions with particular focus on the role of dietary fat in prevention of chronic diseases. She has in total published 43 papers (H-index of 18).
Dr. Ferdinand Molnár: Senior researcher at the School of Pharmacy, Institute of Biopharmacy, University of Eastern Finland. The main research interests of Dr. Molnár are the molecular structure of nuclear receptor proteins and their natural and synthetic ligands, on which he published more than 20 papers (H-index 14). Together with Prof. Carlberg he published the Springer textbook "Mechanisms of gene regulation".    

Textul de pe ultima copertă

The fascinating area of Nutrigenomics describes this daily communication between diet, food and nutrients, their metabolites and our genome. This book describes how nutrition shapes human evolution and demonstrates its consequences for our susceptibility to diseases, such as diabetes and atherosclerosis. Inappropriate diet can yield stress for our cells, tissues and organs and then it is often associated with low-grade chronic inflammation. Overnutrition paired with physical inactivity leads to overweight and obesity and results in increased burden for a body that originally was adapted for a life in the savannas of East Africa. Therefore, this textbook does not discuss a theoretical topic in science, but it talks about real life, and our life-long “chat” with diet. We are all food consumers, thus each of us is concerned by the topic of this book and should be aware of its mechanisms.
The purpose of this book is to provide an overview on the principles of nutrigenomicsand their relation to health or disease. We are not aiming to compete with more comprehensive textbooks on molecular nutrition, evolutionary biology, genomics, gene regulation or metabolic diseases, but rather will focus on the essentials and will combine, in a compact form, elements from different disciplines. In order to facilitate the latter, we favor a high figure-to-text ratio following the rule “a picture tells more than thousand words”.        
The content of this book is based on the lecture course “Nutrigenomics”, which is held since 2003 once per year by Prof. Carlberg at the University of Eastern Finland in Kuopio. The book is subdivided into three sections and twelve chapters. Following the "Introduction" there are sections on the "Molecular genetic basis" and the "Links to disease", which take a view on nutrigenomics from the perspective of molecular mechanisms or from the causes of metabolic diseases, respectively.
Besides its value as a textbook, Nutrigenomics will be a usefull reference for individuals working in biomedicine.

Caracteristici

Written by experts with 12 years lecturing experience on the topic Is the first textbook on nutrigenomics Provides a high figure to text ratio