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Ophthalmic Drug Delivery Systems de Ashim K. Mitra

Ophthalmic Drug Delivery Systems

Editat de Ashim K. Mitra
en Limba Engleză Paperback – 2 dec 2019
The second edition of this text assembles significant ophthalmic advances and encompasses breakthroughs in gene therapy, ocular microdialysis, vitreous drug disposition modelling, and receptor/transporter targeted drug delivery.
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Specificații

ISBN-13: 9780367446765
ISBN-10: 0367446766
Pagini: 847
Dimensiuni: 152 x 229 x 38 mm
Greutate: 0.45 kg
Ediția:2nd edition
Editura: CRC Press
Colecția CRC Press

Public țintă

Academic and Professional Practice & Development

Cuprins

I: Fundamental Considerations 1. Overview of Ocular Drug Delivery 2. Membrane Transport Processes in the Eye 3. General Considerations in Ocular Drug Delivery II: Transport Models in Ocular Drug Delivery 4. Ocular Drug Transfer following Systemic Drug Administration 5. Ocular Pharmacokinetics and Pharmacodynamics 6. Mathematical Modeling of Drug Distribution in the Vitreous Humor 7. Anterior Segment Microdialysis 8. Posterior Segment Microdialysis III: Drug Delivery Systems 9. Ocular Penetration Enhancers 10. Corneal Collagen Shields for Ocular Drug Delivery 11. The Noncorneal Route in Ocular Drug Delivery 12. Ocular Iontophoresis 13. Mucoadhesive Polymers in Ophthalmic Drug Delivery 14. Microparticles and Nanoparticles in Ocular Drug Delivery 15. Dendrimers: An Innovative and Enhanced Ocular Drug Delivery System 16. Ocular Delivery and Therapeutics of Proteins and Peptides 17. Retinal Disease Models for Development of Drug and Gene Therapies 18. New Experimental Therapeutic Approaches for Degenerative Diseases of the Retina 19. Gene, Oligonucleotide, and Ribozyme Therapy in the Eye IV: Regulatory Aspects 20. Regulatory Considerations 21. Patent Considerations

Descriere

This book investigates the fundamental considerations in ocular drug delivery and discusses the latest techniques such as microdialysis and models of ocular drug disposition. It stresses that simple instillation of drug solution in the cul-de-sac is not acceptable and newer systems are needed.