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Organelles in Disease: Reviews of Physiology, Biochemistry and Pharmacology, cartea 185

Editat de Stine Helene Falsig Pedersen, Diane L. Barber
en Limba Engleză Paperback – 28 ian 2024
This book sheds light on how dysregulated organelle functions contribute to the pathology and progression of human diseases. To offer a broad perspective, they discuss basic, translational, and clinical aspects across scales, from molecules to cells, tissues and organisms. Rather than providing a comprehensive introduction to the field, the authors focus on recent advances in organelle research, with each chapter inviting readers to consider today’s key questions in the respective field.

This book reviews the endoplasmic reticulum, Golgi Appartus, Lysosomes and other membrane-enclosed organelles, demonstrating how their dysregulated function contributes to various pathologies. The chapters not only offer a platform for new perspectives but also stimulate further investigations.

Given the translational nature of this subject, this book is a valuable resource for physiologists and clinicians alike.

Chapter "Lipid Droplets in Cancer" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

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Specificații

ISBN-13: 9783031225970
ISBN-10: 303122597X
Pagini: 276
Ilustrații: VII, 276 p. 50 illus., 25 illus. in color.
Dimensiuni: 155 x 235 mm
Greutate: 0.4 kg
Ediția:1st ed. 2023
Editura: Springer International Publishing
Colecția Springer
Seria Reviews of Physiology, Biochemistry and Pharmacology

Locul publicării:Cham, Switzerland

Cuprins

Golgi pH and Ion Homeostasis in Health and Disease.- Stress Granules in Cancer.- Lipid Droplets in Cancer.- Patterns of Ciliation and Ciliary Signaling in Cancer.- Targeting Cancer Lysosomes with Good Old Cationic Amphiphilic Drugs.- Cancer-Related Increases and Decreases in Calcium Signaling at the Endoplasmic Reticulum-Mitochondria Interface (MAMs).- Endosomal Acid-Base Homeostasis in Neurodegenerative Diseases.- Endolysosomal Disorders Affecting the Proximal Tubule of the Kidney: New Mechanistic Insights and Therapeutics.- Endo-Lysosomal Cation Channels and Infectious Diseases.

Textul de pe ultima copertă

Golgi pH and Ion Homeostasis in Health and Disease 
Elham Khosrowabadi and Sakari Kellokumpu

Stress Granules in Cancer 
Min-Seok Song and Elda Grabocka
Lipid Droplets in Cancer
Toni Petan
Patterns of Ciliation and Ciliary Signaling in Cancer
Anna A. Kiseleva, Anna S. Nikonova, and Erica A. Golemis
Targeting Cancer Lysosomes with Good Old Cationic Amphiphilic Drugs 
Anne-Marie Ellegaard, Peter Bach, and Marja Jäättelä
Cancer-Related Increases and Decreases in Calcium Signaling at the Endoplasmic Reticulum-Mitochondria Interface (MAMs) 
Alberto Danese, Saverio Marchi, Veronica Angela Maria Vitto, Lorenzo Modesti, Sara Leo, Mariusz R. Wieckowski, Carlotta Giorgi, and Paolo Pinton
Endosomal Acid-Base Homeostasis in Neurodegenerative Diseases 
Hari Prasad and RajiniRao

Endolysosomal Disorders Affecting the Proximal Tubule of the Kidney: New Mechanistic Insights and Therapeutics
Beatrice Paola Festa, Marine Berquez, Daniela Nieri, and Alessandro Luciani

Endo-Lysosomal Cation Channels and Infectious Diseases 
Yu-Kai Chao, Sui-Yuan Chang, and Christian Grimm

Chapter "Lipid Droplets in Cancer" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Caracteristici

Connects basic cell biology with medical application opportunities Provides insights from both laboratory and clinical research Contributes to a progessive scientific discussion in molecular medicine