Organofluorine Compounds in Biology and Medicine
Autor V Prakash Reddyen Limba Engleză Hardback – 27 ian 2015
- Covers the synthesis, biochemical, and therapeutic applications of organofluorine compounds
- Offers a complete text on biochemically relevant organofluorine compounds and their synthesis and mechanistic pathways
- Provides one of the first major reference books on the biological and medicinal applications of organofluorine chemistry
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Specificații
ISBN-13: 9780444537485
ISBN-10: 0444537481
Pagini: 330
Ilustrații: 20 illustrations
Dimensiuni: 152 x 229 x 32 mm
Greutate: 0.66 kg
Editura: ELSEVIER SCIENCE
ISBN-10: 0444537481
Pagini: 330
Ilustrații: 20 illustrations
Dimensiuni: 152 x 229 x 32 mm
Greutate: 0.66 kg
Editura: ELSEVIER SCIENCE
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Public țintă
This book suits a wide audience, including organic chemists, physical organic chemists, synthetic chemists, medicinal and pharmaceutical chemists, organometallic chemists, biologists, and graduate and post graduate students.Cuprins
1. Introduction: General aspects of organofluorine compounds2. C-F bond strengths3. Effect of the neighboring C-F bonds on the C-H bond dissociation energies4. Effect of fluorine on the acidity and basicity5. Effect of fluorine on the metabolic stability6. Effect of fluorine on the bioavailability7. Positron emission tomography (PET) tracers8. 19F NMR Spectroscopic techniques for probing biochemical mechanisms9. Summary and outlook