In this issue of Oral and Maxillofacial Surgery Clinics, guest editor Dr. Susana Heredero brings her considerable expertise to the topic of Perforator Flaps for Head and Neck Reconstruction. Top experts in the field discuss every major local and regional flap technique, including articles on functional perspectives in tongue reconstruction based on perforator free flap; the ALT flap in head and neck reconstruction; the evolution of imaging on reconstructive microsurgery for perforator flaps harvesting; the role of CTA in perforator flap planning; and more.