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Persister Cells and Infectious Disease de Kim Lewis

Persister Cells and Infectious Disease

Editat de Kim Lewis
en Limba Engleză Hardback – 26 noi 2019
This volume is a collection of chapters from the leading experts in the relatively new and burgeoning field of persister cell studies. Persisters play a leading role in the recalcitrance of chronic infections, and enable the development of classical antibiotic resistance. The focus of the book is on studies that provide an understanding of the mechanisms of persister formation, antibiotic tolerance and role in disease, at the molecular level. 
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Specificații

ISBN-13: 9783030252403
ISBN-10: 303025240X
Pagini: 370
Ilustrații: X, 295 p. 34 illus., 28 illus. in color.
Dimensiuni: 155 x 235 mm
Greutate: 0.61 kg
Ediția:1st ed. 2019
Editura: Springer International Publishing
Colecția Springer
Locul publicării:Cham, Switzerland

Cuprins

1. Evolution under antibiotic treatments: interplay between antibiotic persistence, tolerance and resistance.- 2. Antibiotic persisters and relapsing Salmonella enterica infections.- 3. The Biology of Persister Cells in E. coli.- 4. Persister Formation and Antibiotic Tolerance of Chronic Infections.- 5. Persister formation driven by TisB-dependent membrane depolarization.- 6. Toxin-antitoxin systems and persistence.- 7. Nutrient depletion and bacterial persistence.- 8. Genetic determinants of persistence in Escherichia coli.- 9. Persister resuscitation.- 10. Host-pathogen interactions influencing Mycobacterium tuberculosis persistence and drug tolerance.- 11. Drug susceptibility of individual mycobacterial cells.- 12. Antimicrobial drug discovery against persisters.  

Notă biografică

Professor Kim Lewis, Northeastern University Boston, Massachusetts, USA

Textul de pe ultima copertă

This volume is a collection of chapters from the leading experts in the relatively new and burgeoning field of persister cell studies. Persisters play a leading role in the recalcitrance of chronic infections, and enable the development of classical antibiotic resistance. The focus of the book is on studies that provide an understanding of the mechanisms of persister formation, antibiotic tolerance and role in disease, at the molecular level.

Caracteristici

Provides an understanding of the mechanisms of persister formation Gives an insight into the role of persisters in infectious disease Discusses the aspects of persister formation in antibiotic resistence