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Pharmaceutical Photostability and Stabilization Technology

Editat de Joseph T. Piechocki, Karl Thoma
en Limba Engleză Hardback – 18 sep 2006
Based on a training course developed by Dr. Joseph T. Piechocki and other experts in this field whose contributions appear in this book for two International Meetings on the Photostability of Drugs and Drug Products, this text clarifies the guidelines set by the International Conference on Harmonization (ICH) and provides a comprehensive background in the scientific principles involved in photostability testing.  Presenting the advantages and disadvantages of various procedures so the reader can select and utilize the most appropriate technique best-suited to their needs, this source includes references to current literature in the field and offers an opinion on future opportunities and challenges.
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Specificații

ISBN-13: 9780824759247
ISBN-10: 0824759249
Pagini: 445
Ilustrații: 235 b/w images, 53 tables, 39 halftones and 59 equations
Dimensiuni: 152 x 229 x 29 mm
Greutate: 1.03 kg
Ediția:1
Editura: CRC Press
Colecția CRC Press

Public țintă

Academic and Professional Practice & Development

Cuprins

History of Pharmaceutical Photostability Development.  The ICH  Photostability Guideline: A Discussion of Experimental Conditions.  Terminology.  Basic Principles of Drug Photostability Testing.  Spectra.  Sources.  Glasses, Filters, and Containers.  Chemical Actinometry.  Radiometry/Photometry.  Sample Presentation for Photostability Studies: Problems and Solutions.  Determining the Kinetics and Mechanism of a Photochemical Reaction.  Unexpected Photochemistry in Pharmaceutical Products:  A Review on the Role of Diluents, Excipients, and Product Components in Promoting Pharmaceutical Photochemistry.  Chambers and Mapping.  Current Methods for the Analytical Investigation of the Photodegradation of Active Pharmaceutical Ingredients and Products.  Photostabilization by Packaging.  Photostabilization of Solid and Semisolid Dosage Forms.  Photostability Studies of Solutions and Methods of Preventing Photodegradation.  Photostability of Cosmetic Screens.  Photodegradation and Photoprotection in Clinical Practice.

Notă biografică

Joseph T. Piechocki, Karl Thoma

Descriere

Based on a training course developed by Dr. Joseph T. Piechocki and other experts in this field whose contributions appear in this book for two International Meetings on the Photostability of Drugs and Drug Products, this text clarifies the guidelines set by the International Conference on Harmonization (ICH) and provides a comprehensive background in the scientific principles involved in photostability testing.  Presenting the advantages and disadvantages of various procedures so the reader can select and utilize the most appropriate technique best-suited to their needs, this source includes references to current literature in the field and offers an opinion on future opportunities and challenges.