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Pharmaceutical Water: System Design, Operation, and Validation, Second Edition

Autor William V. Collentro
en Limba Engleză Hardback – 21 dec 2010
A major new work on all aspects of water, the most used raw material ingredient in the pharmaceutical and biotechnology industries—used as an excipient in pharmaceutical formulations, as a cleaning agent, and as a separately packaged product diluent.
Drawing on the author’s extensive field experience with more than 400 pharmaceutical and related water purification systems, the text’s numerous case studies illuminate the best and worst of water system design and operation.
The expanded Second Edition also includes new chapters that discuss:
  • passivation and electropolishing
  • rouging
  • ozone systems and accessories
  • USP purified water and water for injection
  • individual component process and instrumentation diagram (P&IDs) with control interface
  • documentation and specification requirements
  • systems installation, start-up, and commissioning
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Specificații

ISBN-13: 9781420077827
ISBN-10: 1420077821
Pagini: 478
Ilustrații: 146 black & white illustrations
Dimensiuni: 178 x 254 x 33 mm
Greutate: 2.15 kg
Ediția:Revizuită
Editura: CRC Press
Colecția CRC Press
Locul publicării:Boca Raton, United States

Public țintă

Academic, Professional, and Professional Practice & Development

Cuprins

Introduction. Impurities in raw water. Pretreatment techniques. Ion removal techniques—reverse osmosis. Ion removal techniques—ion exchange. Additional ion removal techniques. Distillation and Pure Steam generation. Storage systems and accessories. Ozone systems and accessories. Polishing components. Distribution systems—design, installation, and material selection. Controls and instrumentation. System design and specification guidelines. System installation, start-up, and commissioning. System validation.

Recenzii

"This second edition has been significantly revised and updated from the first edition. The author's extensive work experience in this field is reflected throughout the book, which will serve as an excellent reference for anyone involved in manufacturing pharmaceutical waters." - Doody's Review Service 

Descriere

Water is the most used raw material ingredient in the pharmaceutical and biotechnology industries. Drawing on the author’s extensive field experience with more than 400 pharmaceutical and related water purification systems, this volume provides numerous case studies to illuminate the best and worst of water system design and operation. Topics include passivation and electropolishing, rouging, ozone systems and accessories, USP purified water and water for injection, and individual component process and instrumentation diagram (P&IDs) with control interface. The book also examines documentation and specification requirements and systems installation, start-up, and commissioning.