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Pharmacokinetics for the Pharmaceutical Scientist de John G. Wagner

Pharmacokinetics for the Pharmaceutical Scientist

Autor John G. Wagner
en Limba Engleză Paperback – 7 oct 2019
Major presentation of pharmacokinetics by a leading international expert. Methods for: estimating drug disposition parameters from data obtained after intravascular or extravascular drug administration, estimating rate and extent of drug bioavailability, and comparing rate and extent of drug availability following administration of several different dosage forms of a drug.
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Specificații

ISBN-13: 9780367402402
ISBN-10: 0367402408
Pagini: 336
Dimensiuni: 152 x 229 mm
Greutate: 0.45 kg
Ediția:1
Editura: CRC Press
Colecția CRC Press

Public țintă

Academic and Professional Practice & Development

Cuprins

Simple Linear Models More Complicated Linear Models Complicated Linear Models Linear Multicompartment Disposition Parameters from Extravascular Downslope C,T Data Noncompartmental and System Analysis Linear Multiple Dose Equations Simple Nonlinear Models More Complicated Nonlinear Models Urinary Excretion Absorption Analysis and Bioavailability Physiological Pharmacokinetics Relationship between Physiologically Based Flow Models and Usual Compartment Models Protein Binding Pharmacokinetic Pharmacodynamic Modelling Metabolic Kinetics Laplace Derivation of Linear Pharmacokinetic Equations Measures of Fit Appendix Index 175 Figures and Schematics, 51 Tables, 134 References

Recenzii

"This is a very complete book on modeling the pharmacokinetics of drugs. . . It is one of the very few advanced texts in the field, written by one of the founders of the field and is written with a distilled insight that can only be obtained from years of experience in the field. I highly recommend it."
--Elke Lipka for Pharmaceutical News

Descriere

A major presentation of pharmacokinetics by a leading international expert, this is a complete book on modeling the pharmacokinetics of drugs. It provides methods for: estimating drug disposition parameters from data obtained after intravascular or extravascular drug administration, estimating rate and extent of drug bioavailability, and comparing rate and extent of drug availability following administration of several different dosage forms of a drug. Authored by one of the founders of the field and written with insight that can only be obtained from years of experience, it is one of the very few advanced texts in the field.