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Pharmacological Assays of Plant-Based Natural Products de Thangaraj Parimelazhagan

Pharmacological Assays of Plant-Based Natural Products: Progress in Drug Research, cartea 71

Autor Thangaraj Parimelazhagan
en Limba Engleză Paperback – 31 mar 2018
This volume provides information on how to select and screen plants for their medicinal properties. It describes phytopharmacological techniques for extracting and qualitatively and quantitatively analyzing a plant’s phytochemicals. After a detailed in vitro investigation including nutritional and anti-nutritional analyses, medicinal properties were tested with various in vivo models for anti-inflammatory, analgesic, anti-pyretic, anticancer and anti-diabetic properties, as well as wound healing, neurodegenerative diseases, etc. Compound identification and purification techniques include, among others, TLC and column chromatography, as well as molecular docking with specific proteins.


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Specificații

ISBN-13: 9783319800202
ISBN-10: 3319800205
Ilustrații: XV, 188 p.
Dimensiuni: 155 x 235 mm
Greutate: 0.3 kg
Ediția:Softcover reprint of the original 1st ed. 2016
Editura: Springer International Publishing
Colecția Springer
Seria Progress in Drug Research

Locul publicării:Cham, Switzerland

Cuprins

1. Extraction of plant material.- 2. Critical aspects of purification and impurities in natural product extracts. 3. In vitro antioxidant assays.- 4. In vivo antioxidant assays.- 5. Quantification assays.- 6. Anti-nutritional factors.- 7. Anti-inflammatory activity.- 8. Antipyretic activity.- 9. Inflammation bowel disease.- 10. Anti-arthritic activity.- 11. Evaluation of analgesic potential.- 12. Anti-diarrhoeal activity.- 13. Anti-ulcer activity.- 14. In vitro anti-diabetic activity.- 15. In vivo anti-diabetic activity.- 16. Hepatoprotective property.- 17. Antitumor activity.- 18. In vivo wound healing studies.- 19. Determination of cytotoxicity.- 20. Evaluation of bioavailability.- 21. Molecular identification by DNA barcoding.- 22. Molecular docking of bioactive compounds against BRCA and COX proteins.
 

 

 

 

Notă biografică

Parimelazhagan Thangaraj is aProfessor in the Department of Botany, Bharathiar University, Coimbatore – 641046, India. His field of specialization is Bioprospecting of Medicinal Plants. He is currently engaged in compilation and documentation on available knowledge onvaluable plant resources to prove their utility scientifically through detailedphytochemical, biological and pharmacological investigations.

Textul de pe ultima copertă

This volume provides information on howto select and screen plants for their medicinal properties. It describes phytopharmacologicaltechniques for extracting and qualitatively and quantitatively analyzing aplant’s phytochemicals. After a detailed in vitro investigation including nutritionaland anti-nutritional analyses, medicinal properties were tested with various invivo models for anti-inflammatory, analgesic, anti-pyretic, anticancer andanti-diabetic properties, as well as wound healing, neurodegenerative diseases,etc. Compound identification and purification techniques include, among others,TLC and column chromatography, as well as molecular docking with specificproteins.

Caracteristici

Discusses techniques which are applicable in phytopharmacology Presents protocols which are structured step by step ensuring easy reproducibility Is easy to follow and understand Includes supplementary material: sn.pub/extras