Pharmacology of the Blood Brain Barrier: Targeting CNS Disorders: Advances in Pharmacology, cartea 71
Thomas P. Davisen Limba Engleză Hardback – 28 sep 2014
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Specificații
ISBN-13: 9780128002827
ISBN-10: 0128002824
Pagini: 512
Dimensiuni: 152 x 229 x 38 mm
Editura: ELSEVIER SCIENCE
Seria Advances in Pharmacology
ISBN-10: 0128002824
Pagini: 512
Dimensiuni: 152 x 229 x 38 mm
Editura: ELSEVIER SCIENCE
Seria Advances in Pharmacology
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Cuprins
1. ABC Transporter Regulation by Signaling at the Blood–Brain Barrier: Relevance to Pharmacology
David S. Miller
2. P-glycoprotein Trafficking as a Therapeutic Target to Optimize CNS Drug Delivery
Thomas P. Davis, Lucy Sanchez-Covarubias and Margaret E. Tome
3. Functional Expression of Drug Transporters in Glial Cells: Potential Role on Drug Delivery to the CNS
Tamima Ashraf, Amy Kao and Reina Bendayan
4. Blood–Brain Barrier Na Transporters in Ischemic Stroke
Martha E. O’Donnell
5. Transcytosis of Macromolecules at the Blood–Brain Barrier
Jane E. Preston, N. Joan Abbott and David J. Begley
6. Drug Delivery to the Ischemic Brain
Brandon J. Thompson and Patrick T. Ronaldson
7. Delivery of Chemotherapeutics Across the Blood–Brain Barrier: Challenges and Advances
Nancy D. Doolittle, Leslie L. Muldoon, Aliana Y. Culp and Edward A. Neuwelt
8. Delivery of Antihuman African Trypanosomiasis Drugs Across the Blood–Brain and Blood–CSF Barriers
Gayathri N. Sekhar, Christopher P. Watson, Mehmet Fidanboylu, Lisa Sanderson and Sarah A. Thomas
9. Delivery of Therapeutic Peptides and Proteins to the CNS
Therese S. Salameh and William A. Banks
10. Engineering and Pharmacology of Blood–Brain Barrier-Permeable Bispecific Antibodies
Danica Stanimirovic, Kristin Kemmerich, Arsalan S. Haqqani and Graham K. Farrington
11. Pharmacological Significance of Prostaglandin E2 and D2 Transport at the Brain Barriers
Masanori Tachikawa, Ken-ichi Hosoya and Tetsuya Terasaki
12. Steroids and the Blood–Brain Barrier: Therapeutic Implications
Ken A. Witt and Karin E. Sandoval
13. Combination Approaches to Attenuate Hemorrhagic Transformation After tPA Thrombolytic Therapy in Patients with Poststroke Hyperglycemia/Diabetes
Xiang Fan, Yinghua Jiang, Zhanyang Yu, Jing Yuan, Xiaochuan Sun, Shuanglin Xiang, Eng H. Lo and Xiaoying Wang
14. Aging, the Metabolic Syndrome, and Ischemic Stroke: Redefining the Approach for Studying the Blood–Brain Barrier in a Complex Neurological Disease
Brandon P. Lucke-Wold, Aric F. Logsdon, Ryan C. Turner, Charles L. Rosen and Jason D. Huber
15. Drug Abuse and the Neurovascular Unit
Richard D. Egleton and Thomas Abbruscato
David S. Miller
2. P-glycoprotein Trafficking as a Therapeutic Target to Optimize CNS Drug Delivery
Thomas P. Davis, Lucy Sanchez-Covarubias and Margaret E. Tome
3. Functional Expression of Drug Transporters in Glial Cells: Potential Role on Drug Delivery to the CNS
Tamima Ashraf, Amy Kao and Reina Bendayan
4. Blood–Brain Barrier Na Transporters in Ischemic Stroke
Martha E. O’Donnell
5. Transcytosis of Macromolecules at the Blood–Brain Barrier
Jane E. Preston, N. Joan Abbott and David J. Begley
6. Drug Delivery to the Ischemic Brain
Brandon J. Thompson and Patrick T. Ronaldson
7. Delivery of Chemotherapeutics Across the Blood–Brain Barrier: Challenges and Advances
Nancy D. Doolittle, Leslie L. Muldoon, Aliana Y. Culp and Edward A. Neuwelt
8. Delivery of Antihuman African Trypanosomiasis Drugs Across the Blood–Brain and Blood–CSF Barriers
Gayathri N. Sekhar, Christopher P. Watson, Mehmet Fidanboylu, Lisa Sanderson and Sarah A. Thomas
9. Delivery of Therapeutic Peptides and Proteins to the CNS
Therese S. Salameh and William A. Banks
10. Engineering and Pharmacology of Blood–Brain Barrier-Permeable Bispecific Antibodies
Danica Stanimirovic, Kristin Kemmerich, Arsalan S. Haqqani and Graham K. Farrington
11. Pharmacological Significance of Prostaglandin E2 and D2 Transport at the Brain Barriers
Masanori Tachikawa, Ken-ichi Hosoya and Tetsuya Terasaki
12. Steroids and the Blood–Brain Barrier: Therapeutic Implications
Ken A. Witt and Karin E. Sandoval
13. Combination Approaches to Attenuate Hemorrhagic Transformation After tPA Thrombolytic Therapy in Patients with Poststroke Hyperglycemia/Diabetes
Xiang Fan, Yinghua Jiang, Zhanyang Yu, Jing Yuan, Xiaochuan Sun, Shuanglin Xiang, Eng H. Lo and Xiaoying Wang
14. Aging, the Metabolic Syndrome, and Ischemic Stroke: Redefining the Approach for Studying the Blood–Brain Barrier in a Complex Neurological Disease
Brandon P. Lucke-Wold, Aric F. Logsdon, Ryan C. Turner, Charles L. Rosen and Jason D. Huber
15. Drug Abuse and the Neurovascular Unit
Richard D. Egleton and Thomas Abbruscato
Recenzii
"...it will be of immense value to those working in the area of CNS drug research or development and will also have a place in the libraries of academic institutions." --The Pharmaceutical Journal, November 2014