Phylogenomics: A Primer

Autor Rob DeSalle, Michael Tessler, Jeffrey Rosenfeld

en Limba Engleză Paperback – 19 aug 2020

Phylogenomics: A Primer, Second Edition is for advanced undergraduate and graduate biology students studying molecular biology, comparative biology, evolution, genomics, and biodiversity. This book explains the essential concepts underlying the storage and manipulation of genomics level data, construction of phylogenetic trees, population genetics, natural selection, the tree of life, DNA barcoding, and metagenomics. The inclusion of problem-solving exercises in each chapter provides students with a solid grasp of the important molecular and evolutionary questions facing modern biologists as well as the tools needed to answer them.

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Specificații

ISBN-13: 9780367028497
ISBN-10: 0367028492
Pagini: 400
Ilustrații: 165
Dimensiuni: 210 x 280 x 27 mm
Greutate: 0.93 kg
Ediția:Nouă
Editura: CRC Press
Colecția CRC Press

Public țintă

Postgraduate, Professional Reference, and Undergraduate

Cuprins

Preface. Acknowledgements. Foundations of Phylogenomics. What is Phylogenomics?. The Biology and Sequencing of Genetic Information: DNA, RNA, and Proteins. Evolutionary Principles: Populations and Trees. Data. Data Storage—The Basics. Sequence Alignment and Searching Sequence. Databases. Multiple Alignments. Genome Sequencing and Annotation. Genomics Databases: Genomes and Transcriptomes. Amplicon Databases: BoLD and Bacterial 16S rDNA Databases. Phylogenetic/Phylogenomic Analysis. Introduction to Tree Building. Distance and Clustering. Maximum Likelihood. Search Strategies and Robustness. Rate Heterogeneity, Long Branch Attraction, and Likelihood Models. Bayesian Approaches in Phylogenetics. Incongruence of Gene Trees. Phylogenetic Programs and Websites. Population Genomics. Population Genetics and Genomes. Population Genomics Approaches. Detecting Natural Selection: The Basics. Refining the Approach to Natural Selection at the Molecular Level. Phylogenomics in Action. Constructing Phylogenomic Matrices. Phylogenomics and the Tree of Life. Comparative Genomics. Environmental DNA (eDNA). Phylogenomic Approaches to Understanding Gene Function and Evolution. Index.

Recenzii

"This is a top-quality book that is timely and engaging. It is a necessary and
welcome update of the first edition that is now several years old. I would
recommend it to my colleagues teaching this material without reservation."
- Mark F. Sanders, PhD, UC Davis College of Biological Sciences

Descriere

Phylogenomics: A Primer, 2nd edition is for advanced undergraduate and graduate biology students and explains the essential concepts underlying the storage and manipulation of genomics level data, construction of phylogenetic trees, population genetics, natural selection, the tree of life, DNA barcoding, and metagenomics.

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