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Proceedings of the Research Symposium on Complexes of Biologically Active Substances with Nucleic Acids and Their Modes of Action: Held at the Walter Reed Army Institute of Research Washington, 16–19 March 1970: Progress in Molecular and Subcellular Biology, cartea 2

Autor Robert E. Rhoads
en Limba Engleză Paperback – 6 ian 2012

Din seria Progress in Molecular and Subcellular Biology

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Specificații

ISBN-13: 9783642651434
ISBN-10: 3642651437
Pagini: 412
Ilustrații: X, 400 p.
Dimensiuni: 170 x 244 x 22 mm
Greutate: 0.66 kg
Ediția:Softcover reprint of the original 1st ed. 1971
Editura: Springer Berlin, Heidelberg
Colecția Springer
Seria Progress in Molecular and Subcellular Biology

Locul publicării:Berlin, Heidelberg, Germany

Public țintă

Research

Cuprins

Complexes of Biologically Active Substances with Nucleic Acids — Yesterday, Today, Tomorrow.- Antibiotics and Nucleic Acids.- Kinetics of Binding of Drugs to DNA.- The Binding of Actinomycin D to DNA.- Interaction of Antitumor Antibiotics with DNA: Studies on Sibiromycin.- Anthramyein.- Inhibition of RNA Synthesis by Quinone Antibiotics.- Changes in the Properties of Ribosomes and Transfer RNA Induced by Inhibitors of Protein Synthesis.- Antimalarials and Nucleic Acids.- Chloroquine Binding to Nucleic Acids: Characteristics, Biological Consequences, and a Proposed Binding Model for the interaction.- A Preliminary Nuclear Magnetic Resonance Study of the Effect of pH on the Structure of Chloroquine Diphosphate.- Effects of Chlotoquine and Some Related Compounds on Aminoacylation of Transfer Ribonucleic Acids.- Interaction of Antimalarial Aminoquinolines (Primaquine, Pentaquine, and Chloroquine) with Nucleic Acids, and Effects onVarious Enzymatic Reactions in Vitro.- Interpretation of Antimalarial Activity in Terms of Regression Analyses, Molecular Orbital Calculations, and Theory of DNA-Drug Binding.- Alkaloids, Natural Poly amines and DNA.- Interactions of Alkaloids with DNA.- Physical Studies on the Interaction of Lysergic Acid Diethylamide and Trypanocidal Dyes with DNA and DNA-Containing Genetic Material.- Comments on the Interaction of LSD with DNA.- The Interaction of Polyamines with Nucleic Acids.- Intercalation into Supercoiled DNA.- The Use of Intercalative Dyes in the Study of Closed Circular DNA.- Binding of Drugs to Supercoiled Circular DNA: Evidence for and against Intercalation.- Synthetic Drugs and Dyes Binding to Nucleic Acids.- Mode of Action of Miracil D.- Molecular Biological Effects of Nitroakridin 3582 and Related Compounds.- Binding ofNaphthylvinylpyridines to DNA.- Formation of Yeast Mitochondria: V. Ethidium Bromide as a Probe for the Functions of Mitochondrial DNA.- Studies on tRNA Structure Using Covalently and Noncovalently Bound Fluorescent Dyes.- Antimutagens.- Antimutagens and Antimicrobial Drug Resistance.- Some Studies on the Antimutagenic Action of Polyamines.- Carcinogens and Nucleic Acids.- Interaction and Linkage of Polycyclic Hydrocarbons to Nucleic Acids.- Interaction of N-2-Acetylaminofluorene with RNA.- The Natural State of DNA.- Intercalability, the ? Transition, and the State of DNA in Nature.