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Protein Misfolding Diseases: Advances in Protein Chemistry and Structural Biology, cartea 148

Rossen Donev Ajaz A. Bhat
en Limba Engleză Hardback – dec 2025
Protein Misfolding Diseases, delves into the intricate molecular mechanisms behind a class of devastating disorders caused by abnormal protein folding. This comprehensive book explores the pathophysiology, diagnostic challenges, and therapeutic strategies associated with a spectrum of protein misfolding diseases, including neurodegenerative conditions like Alzheimer's, Parkinson's, and prion diseases, as well as systemic amyloidoses. From unraveling the underlying protein aggregation processes to discussing cutting-edge research on disease-modifying therapies, this book provides a multidisciplinary perspective on understanding and combating protein misfolding diseases. With contributions from leading experts in the field, it serves as a valuable resource for researchers, clinicians, and students seeking to deepen their knowledge of these complex and challenging disorders.

  • Provides a thorough examination of protein misfolding diseases, covering various types of disorders caused by aberrant protein folding
  • Explores the molecular mechanisms underlying protein misfolding and its implications on cellular function and disease progression
  • Focuses on specific protein misfolding disorders such as Alzheimer's disease, Parkinson's disease, prion diseases, and amyloidosis, offering in-depth insights into each condition
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Specificații

ISBN-13: 9780443294143
ISBN-10: 0443294143
Pagini: 488
Dimensiuni: 152 x 229 mm
Editura: ELSEVIER SCIENCE
Seria Advances in Protein Chemistry and Structural Biology


Cuprins

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Bilgimol Chumappumkal Joseph, Nicca Falah, Juan Andres De Pablo-Moreno, Dana H Simmons and Annette von Drygalski
2. TBD
Sarita Montaño
3. TBD
Sreejith Madhavankutty
4. Characterizing Protein Misfolding: Inside and Out
Amritangshu Chakravarty
5. TBD
Krishnamurthy Nakuluri and Vani Gowru
6. TBD
Shahab Uddin, Abdul Ansari, Aamir Ahmad, Lubna Therachiyil, Gazala Anamangadan, Manel Sadok and Hesham M Korashy
7. Longitudinal plasma proteome of vaccinated individuals reveals altered factors associated with blood coagulation and immune responses
Aamir Ahmad
8. TBD
Muzafar Ahmad Macha
9. TBD
Manzoor A. Mir Sr.
10. Heat Shock proteins (HSPs) as chaperones for Oncogenesis
Mayank Singh
11. TBD
Ajaz Ahmad Bhat
12. Protein Misfolding and Cancer: Molecular Insights and Future Perspectives
Sireesha V. Garimella and Geethika Ishani Makka
13. Proteostasis and Pathogenesis: Unraveling the Complexity of Protein Misfolding Disorders
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14. TBD
Surbhi Sharma
15. TBD
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16. Small molecule inhibitors targeting α-synuclein aggregation: Progress and future outlook
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17. Chaperone Machinery in Neurodegeneration: A Spotlight on Protein Misfolding Diseases
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18. Title yet to decide
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19. Calpain- mediated proteolytic cleavage
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