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Rb and Tumorigenesis: Medical Intelligence Unit

Editat de Maurizio Fanciulli
en Limba Engleză Hardback – 17 mar 2006
Rb and Tumorigenesis examines how recent advances have demonstrated the interaction of Rb with chromatin remodeling enzymes. This new title explores the potential roles of these interactions in Rb functions and provides some evidence that distinct Rb co-repressor may target different genes in different phases of the cell cycle.
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Specificații

ISBN-13: 9780387321738
ISBN-10: 038732173X
Pagini: 121
Ilustrații: IX, 121 p.
Dimensiuni: 155 x 235 x 13 mm
Greutate: 0.35 kg
Ediția:2006
Editura: Springer Us
Colecția Springer
Seria Medical Intelligence Unit

Locul publicării:New York, NY, United States

Public țintă

Research

Cuprins

RB as a Positive Transcriptional Regulator during Epithelial Differentiation.- pRb in the Differentiation of Normal and Neoplastic Cells.- Regulation of DNA Replication by the Retinoblastoma Tumor Suppressor Protein.- New Insights into Transcriptional Regulation by Rb.- Regulation of Rb Function by Noncyclin Dependent Kinases.- Diverse Regulatory Functions of the E2F Family of Transcription Factors.- Regulation of E2F-Responsive Genes through Histone Modifications.- Emerging Roles for the Retinoblastoma Gene Family.- Rb and Cellular Differentiation.

Caracteristici

Rb and Tumorigenesis describes the emerging roles of this important tumor suppressor, and its involvement in the control of development, apoptosis and cancer Includes supplementary material: sn.pub/extras