Ty Karos is a young doctor at a New York City hospital. While treating a dying patient, he is exposed to hepatitis C, a life-threatening virus which causes liver damage. The event triggers anxious, hopeless thoughts as Ty struggles with the premise of his own mortality. His Epicurean beliefs and principles, which he has strictly adhered to and drawn strength from over the years, are challenged by this new obstacle, as he leans on his mentor Dr. Hobbes for guidance. Ty reasons that something, or rather someone, is missing from his life- Miranda, a long lost love he met in the Cycladic islands a decade earlier. Hoping she might somehow aid his recovery, he locates her and the two re-unite. Throughout his spiritual journey, Ty questions how best to live, the value of love, and what follows death. In the end, it is these enduring experiences in Ty's troubled life which emerge as his principal reflections in the stream.