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Regression Analysis in Medical Research: for Starters and 2nd Levelers

Autor Ton J. Cleophas, Aeilko H. Zwinderman
en Limba Engleză Paperback – 3 mar 2022
Regression analysis of cause effect relationships is increasingly the core of medical and health research. This work is a 2nd edition of a 2017 pretty complete textbook and tutorial for students as well as recollection / update bench and help desk for professionals.
It came to the authors' attention, that information of history, background, and purposes, of the regression methods addressed were scanty. Lacking information about all of that has now been entirely covered.
The editorial art work of the first edition, however pretty, was less appreciated by some readerships, than were the original output sheets from the statistical programs as used. Therefore, the editorial art work has now been systematically replaced with original statistical software tables and graphs for the benefit of an improved usage and understanding of the methods.
In the past few years, professionals have been flooded with big data. The Covid-19 pandemic gave cause for statistical software companies to foster novel analytic programs better accounting outliers and skewness. Novel fields of regression analysis adequate for such data, like sparse canonical regressions and quantile regressions, have been included.


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Specificații

ISBN-13: 9783030613969
ISBN-10: 3030613968
Pagini: 475
Ilustrații: XV, 475 p. 482 illus., 72 illus. in color.
Dimensiuni: 155 x 235 x 29 mm
Greutate: 0.68 kg
Ediția:2nd ed. 2021
Editura: Springer International Publishing
Colecția Springer
Locul publicării:Cham, Switzerland

Cuprins

Preface.- Continuous Outcome Regressions.- Dichotomous Outcome Regressions.- Confirmative Regressions.- Dichotomous Regressions Other than Logistic and Cox.- Polytomous Outcome Regressions.- Time to Event Regressions other than Traditional Cox.- Analysis of Variance (ANOVA).- Repeated Outcomes Regression Methods.- Methodologies for Better Fit of Categorical Predictors.- Laplace Regressions, Multi- instead of Mono-Exponential Models.- Regressions For Making Extrapolations..- Standardized Regression Coefficients.- Multivariate Analysis of Variance and Canonical Regression.- More on Poisson Regressions.- Regression Trend Testing.- Optimal Scaling and Automatic Linear Regression.- Spline Regressions.- More on Nonlinear Regressions.- Special Forms of Continuous Outcome Regressions.- Regressions for Quantitative Diagnostic Testing.- Regressions, a Panacee or at Least a Widespread Help for Data Analyses.- Regression Trees.- Regressions with Latent Variables.- Partial Correlations.- Functional Data Analysis Basis.- Functional Data Analysis Advanced.- Quantile Regression.- Index.      


Notă biografică

The authors are well-qualified in their field. Professor Zwinderman is past-president of the International Society of Biostatistics (2012-2015), and Professor Cleophas is past-president of the American College of Angiology (2000-2002). 

Professor Zwinderman is one of the Principle Investigators of the Academic Medical Center Amsterdam, and his research is concerned with developing statistical methods for new research designs in biomedical science, particularly integrating omics data, like genomics, proteomics, metabolomics, and analysis tools based on parallel computing and the use of cluster computers and grid computing.   

Professor Cleophas is a member of the Academic Committee of the European College of Pharmaceutical Medicine, that provides, on behalf of 22 European Universities, the Master-ship trainings  "Pharmaceutical Medicine" and "Medicines Development".  

From their expertisethey should be able to make adequate selections of modern methods for clinical data analysis for the benefit of physicians, students, and investigators. The authors have been working and publishing together for 18 years, and their research can be characterized as a continued effort to demonstrate that clinical data analysis is not mathematics but rather a discipline at the interface of biology and mathematics.

The authors as professors and teachers in statistics at universities in The Netherlands and France for the most part of their lives, are concerned, that their students find regression-analyses harder than any other methodology in statistics. This is serious, because almost all of the novel methodologies in current data mining and data analysis include elements of regression-analysis, and they do hope that the current production "Regression Analysis for Starters and 2nd Levelers" will be a helpful companion for the purpose.
 
Five textbookscomplementary to the current production and written by the same authors are 

Statistics applied to clinical studies 5th edition, 2012, 
Machine learning in medicine a complete overview, 2015, 
SPSS for starters and 2nd levelers 2nd edition, 2015, 
Clinical data analysis on a pocket calculator 2nd edition, 2016, 
Modern Meta-analysis, 2017, 
Regression Analysis in Medical Research, 2018, 
Modern Bayesian Statistics in Clinical Research, 2018, 
Analysis of Safety Data of Drug Trials, 2019,
Efficacy Analysis in Clinical Trials, 2019 
All published by Springer

 


Textul de pe ultima copertă

Regression analysis of cause effect relationships is increasingly the core of medical and health research. This work is a 2nd edition of a 2017 pretty complete textbook and tutorial for students as well as recollection / update bench and help desk for professionals.
It came to the authors' attention, that information of history, background, and purposes, of the regression methods addressed were scanty. Lacking information about all of that has now been entirely covered.
The editorial art work of the first edition, however pretty, was less appreciated by some readerships, than were the original output sheets from the statistical programs as used. Therefore, the editorial art work has now been systematically replaced with original statistical software tables and graphs for the benefit of an improved usage and understanding of the methods.

In the past few years, professionals have been flooded with big data. The Covid-19 pandemic gave cause for statisticalsoftware companies to foster novel analytic programs better accounting outliers and skewness. Novel fields of regression analysis adequate for such data, like sparse canonical regressions and quantile regressions, have been included.


 

Caracteristici

Lacking information of the history, background, and purposes has now been entirely covered Editorial art work of the first edition has been systematically replaced with original statistical software tables and graphs for improved usage and understanding of the methods Novel fields of regression analysis adequate for big data, and, particularly, skewed big data, like current Covid-19 data, have been included

Recenzii

“This is a comprehensive book on various types of theoretical, basic, and applied regression analysis in medical research. … There are sufficient examples in each chapter to enable better understanding of theory. … Each chapter has numerous graphs and tables, which are easy to understand and nicely detailed. This is an excellent reference for medical students, researchers in medicine, and healthcare professionals who want either a basic or an advanced understanding and interpretation of all types of regression analysis.” (Timir Paul, Doody's Book Reviews, April, 2018)