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Sphingolipid-Mediated Signal Transduction: Molecular Biology Intelligence Unit

Editat de Yusuf A. Hannun
en Limba Engleză Paperback – 13 noi 2013
Lipid-derived molecules are increasingly appreciated as key regulators of cell responses and signal transduction. Sphingolipid-derived bioactive molecules are emerging as critical regulators of some of the most exciting and, until recently, poorly-understood areas of biology such as growth suppression, programmed cell death and tumor invasion. Written by leading investigators in these areas of study, this book presents a thorough, current and accessible review of how sphingolipids function to regulate these important activities.
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Specificații

ISBN-13: 9783662224274
ISBN-10: 3662224275
Pagini: 212
Ilustrații: XVII, 188 p. 8 illus.
Dimensiuni: 152 x 229 x 11 mm
Greutate: 0.29 kg
Ediția:Softcover reprint of the original 1st ed. 1997
Editura: Springer Berlin, Heidelberg
Colecția Springer
Seria Molecular Biology Intelligence Unit

Locul publicării:Berlin, Heidelberg, Germany

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Research

Cuprins

1. Introduction and Overview.- 2. Ceramide: A Stress Response Mediator Involved in Growth Suppression.- 3. Ceramide and Inflammation.- 4. A Role for Ceramide in Meiosis.- 5. Ceramide, Aging and Cellular Senescence.- 6. Ceramide, a Mediator of Cytosine Arabinoside Induced Apoptosis.- 7. The Use of Cerebroside Synthase Inhibitors as Probes for Assessing the Metabolism and Function of Sphingolipids.- 8. Role of Sphingolipids in Regulating the Phospholipase D Pathway and Cell Division.- 9. Sphingosine-l-Phosphate: Member of a New Class of Lipid Second Messengers.- 10. Functional Roles of Glycosphingolipids and Sphingolipids in Signal Transduction.- 11. Ceramide Synthase and Ceramidases in the Regulation of Sphingoid Base Metabolism.- 12. Ceramidase and Signal Transduction.