Almost 10 years ago, I wrote a book entitled Start-up, what we may still learn from Silicon Valley. If I had to do a second edition, I don't think I'd change much despite all the flaws and blunders of the exercise. Yet one morning in February 2016, I had a look at ten years of supporting start-up entrepreneurs and decided to send again old and also new messages to those that the world of innovation and high-tech entrepreneurship puzzles or interests.