Stroke is common, complicated to manage, and a major health concern worldwide. However, evidence shows that thorough and organized care from teams of health professionals on stroke units leads to substantially fewer deaths and better recovery than other types of care. For all the members of the stroke team, including doctors, nurses, stroke co-ordinators, physiotherapists, occupational therapists, and speech and language therapy members, this handbook provides a holistic approach to the care of patients with transient ischemic attacks (TIA) and stroke. It covers the wide range of knowledge and skills needed to tackle problems that may lead up to, or follow on from a stroke, and follows the course of a patient's 'journey' from diagnosis to life at home, incorporating recent changes in the field of stroke medicine, including the latest clinical trials. For this new edition, practice recommendations have been fully updated in light of the evidence supporting prevention (including early intervention and DOACs), acute care (in particular, thrombectomy and the role of hyperacute stroke units), rehabilitation, and long-term care. Chapter 5 'Neuroimaging in stroke' has been expanded to include new technical developments and the book includes a brand new chapter on cognitive impairment.