Géraldine Masson, Luc Neuville ∙ Carine Bughin ∙ Aude Fayol ∙ Jieping ZhuMulticomponent Syntheses of MacrocyclesThomas J.J. MüllerPalladium-Copper Catalyzed Alkyne Activation as an Entry to Multicomponent Syntheses of HeterocyclesRachel Scheffelaar ∙ Eelco Ruijter ∙ Romano V.A. OrruMulticomponent Reaction Design Strategies: Towards Scaffold and Stereochemical DiversityNicola Kielland ∙ Rodolfo LavillaRecent Developments in Reissert-Type Multicomponent ReactionsJitender B. Bariwal ∙ Jalpa C. Trivedi ∙ Erik V. Van der EyckenMicrowave Irradiation and Multicomponent ReactionsIrini Akritopoulou-Zanze ∙ Stevan W. DjuricApplications of MCR-Derived Heterocycles in Drug Discovery