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Targets of Cancer Diagnosis and Treatment: Ion Transport in Tumor Biology: Reviews of Physiology, Biochemistry and Pharmacology, cartea 183

Editat de Christian Stock, Luis A. Pardo
en Limba Engleză Paperback – 7 mai 2023
This third and final volume in the "Ion Transport in Tumor Biology" collection presents novel diagnostic and therapeutic approaches in cancer based on the exploitation of ion transport proteins. The authors critically examine several transportome members, particularly Na+, K+, Ca2+, and Cl- channels, as well as organic solute carriers regarding their suitability as therapeutic targets. Synergistic effects resulting from the combined use of classical cytostatics with ion transport-inhibiting drugs are pointed out, and the capability of bispecific antibodies to function as anticancer drugs is discussed. 
As readers will also learn, the use of ion channel inhibitors could improve the outcome of radiotherapy because the development of radio-resistance during radiotherapeutic treatment often correlates with increases in the expression levels and conductance of ion channels. The translational topics of this volume form a bridge between biochemical research and therapeutic application.
As part of a three-volume collection, this book will fascinate members of the active research community, as well as clinicians in the cancer field.
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Specificații

ISBN-13: 9783031039966
ISBN-10: 3031039963
Ilustrații: X, 277 p. 30 illus., 20 illus. in color.
Dimensiuni: 155 x 235 mm
Greutate: 0.41 kg
Ediția:1st ed. 2022
Editura: Springer International Publishing
Colecția Springer
Seria Reviews of Physiology, Biochemistry and Pharmacology

Locul publicării:Cham, Switzerland

Cuprins

Targeting Ion Channels for Cancer Treatment: Current Progress and Future Challenges.- Novel Therapeutic Approaches of Ion Channels and Transporters in Cancer.- Ion Channels in Cancer: Orchestrators of Electrical Signaling and Cellular Crosstalk.- Potassium and Chloride Ion Channels in Cancer: A Novel Paradigm for Cancer Therapeutics.- Potassium and Calcium Channel Complexes as Novel Targets for Cancer Research.- Solute Carrier Transportome in Chemotherapy-Induced Adverse Drug Reactions.- Ion Transport and Radioresistance.- Ion Transporting Proteins and Cancer: Progress and Perspectives.

Textul de pe ultima copertă

Targeting Ion Channels for Cancer Treatment: Current Progress and Future Challenges
Alina L. Capatina, Dimitris Lagos, and William J. BrackenburyNovel Therapeutic Approaches of Ion Channels and Transporters in Cancer
Ana Ramírez, Janice García-Quiroz, Luis Aguilar-Eslava, Yesennia Sánchez-Pérez, and Javier Camacho
Ion Channels in Cancer: Orchestrators of Electrical Signaling and Cellular Crosstalk

Jerry J. Fan and Xi Huang
Potassium and Chloride Ion Channels in Cancer: A Novel Paradigm for Cancer Therapeutics

Umberto Banderali, Luigi Leanza, Najmeh Eskandari, and Saverio Gentile
Potassium and Calcium Channel Complexes as Novel Targets for Cancer Research
Marie Potier-Cartereau, William Raoul, Gunther Weber, Karine Mahéo, Raphael Rapetti-Mauss, Maxime Gueguinou, Paul Buscaglia, Caroline Goupille, Nelig Le Goux, Souleymane Abdoul-Azize, Thierry Lecomte, Gaëlle Fromont, Aurélie Chantome, Olivier Mignen, Olivier Soriani, and Christophe Vandier
Solute Carrier Transportome in Chemotherapy-Induced Adverse Drug Reactions
Jason T. Anderson, Kevin M. Huang, Maryam B. Lustberg, Alex Sparreboom, and Shuiying Hu
Ion Transport and Radioresistance
Bastian Roth and Stephan M. Huber
Ion Transporting Proteins and Cancer: Progress and Perspectives
Mustafa B. A. Djamgoz

Caracteristici

Demonstrates how ion channels and transporters could be used as tumor markers Provides novel transport-focused approaches in anti-cancer treatment Opens up new perspectives in treatment strategies for cancer