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Techniques for Downstream process for Biologic Drugs and Vaccines: Developments in Applied Microbiology and Biotechnology

Autor Basanta Kumara Behera
en Limba Engleză Paperback – 3 aug 2023
Techniques for Downstream process for Biologic Drugs and Vaccines provides comprehensive technologies involved in processing postharvest broth to separate the target biological therapeutic products of extracellular or intercellular aspects in nature - to its highest purification form, and to thus make it acceptable to end users. The technologies involved in the post-harvesting of fermented broth are explained in this comprehensive resource in a simplified manner with different case studies to help non-engineering students and scientists easily capture the basic principle of biomass processing technologies and their applications in new projects related to the development and manufacturing of therapeutic bio-products.
As conceptual development of biotechnology has taken new shape and style with the integration of medical sciences, physical science, and engineering, and has thus begun the need for the development of microbial or cell line process technology and application for large-scale isolation and purification of metabolites or vaccines through the fermentation process, this book covers the most important aspects.


  • Provides insights into the conceptual strategic drive for manufacturing innovative biologically derived therapeutic compounds for commercial purposes
  • Focuses on how to execute biopharmaceutical portfolio trends to bring sustainable manufacturing process as per guidelines of international regulatory acts
  • Highlights emerging trends in medical sciences on tissue engineering, regenerative medicine, personalized medicines, and various innovative techniques on immunotherapy to fight against life-threatening diseases
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Specificații

ISBN-13: 9780443191572
ISBN-10: 0443191573
Pagini: 278
Dimensiuni: 191 x 235 x 18 mm
Greutate: 0.6 kg
Editura: ELSEVIER SCIENCE
Seria Developments in Applied Microbiology and Biotechnology


Public țintă

students and research in biotechnology, pharmaceutical sciences, medical sciences, biochemical engineering who want to get into depth in the subject and its future prospective to develop biotechnology-based start-up, as an entrepreneur or working in the front-line in biotechnology industries. business communities in biotechnology-based industry for biologic drugs and vaccines production and marketing. Administrators and decision-making bodies to understand the future prospects of biotechnology by going through the global demand of biological drugs in the international market and it value related to GDP of a specific nation

Cuprins

1. Pre-harvesting Conditions and Planning for Downstream Process2. Downstream Process (Harvested Broth Concentration Phase I3. Biomass Concentrations Phase II4. Release of Intracellular Materials Phase-III5. Extraction of Product of Interest Phase IV6. Viral Vectors for Vaccine Production7. Quality Control 8. Qualities by Design9. Towards Biologics