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The Benefit/Risk Ratio: A Handbook for the Rational Use of Potentially Hazardous Drugs

Autor Hans C. Korting, M. Schafer-Korting
en Limba Engleză Hardback – 24 iul 1998
The use of drugs as remedies for various types of diseases has a long tradition; however, it has only been recently recognized that the value of any given compound must be evaluated in light of its benefit to risk ratio. When prescribing drugs, physicians must look at the big picture of the drug's benefits in relation to its side effects and possible toxicity. The aim of this handbook is to compile data from various authors, providing clinicians with data that will optimize their decision making in selecting effective, low-risk drug treatments. It also provides research workers, including physicians, pharmacists, and basic scientists, with a sound basis for increasing knowledge of the risk/benefit ratios of various drugs.
Includes detailed assessments of the following types of drugs:
  • Antihypertensive agents
  • Diuretics
  • Anti-diabetic drugs
  • Anticonvulsant drugs
  • Drugs for Parkinson's disease
  • Antihistamines and antiserotonins
  • Cytokines and immunomodulators
  • Non-opioid analgesics and anti-inflammatory agents
  • Antibacterial agents
  • Antiviral agents
  • Drugs used in reproductive endocrinology
  • Systemic drugs for skin diseases
  • Topical liposome drugs
  • Topical glucocorticoids
  • Citește tot Restrânge

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    Specificații

    ISBN-13: 9780849327919
    ISBN-10: 0849327911
    Pagini: 398
    Ilustrații: 2 black & white illustrations, 70 black & white tables, 2 black & white halftones
    Dimensiuni: 178 x 254 x 27 mm
    Greutate: 0.93 kg
    Ediția:1
    Editura: CRC Press
    Colecția CRC Press

    Public țintă

    • Pharmacologists
    • Pharmaceutical scientists
    • Toxicologists
    • Physicians
    • Basic scientists

    Cuprins

    The Role and Analysis of Benefit and Risk in the Development of New Drugs. Prediction of the Benefit/Risk Ratio from In Vitro Data. Evaluation of Therapeutic Benefits and Toxicological Risks Using Structure-Activity Relational Expert Systems. Improving the Therapeutic Index Through Unusual Routes of Application: Intra-Arterial Treatment of Liver Metastases. Establishing the Benefit/Risk Ration with Combination Drugs. Improving the Therapeutic Index of Antineoplastic Agents through Additional Drugs. Antihypertensive Agents. Diueretics. Anti-Diabetic Drugs. Anticonvulsant Drugs and Drugs for Parkinson's Disease. Antihistamines and Antiserotonins. Cytokines and Immunomodulators. Non-Opioid Analgesics and Anti-Inflammatory Agents. Toxicity Profile of Liposomal Anthacyclines. Antibacterial Agents. Antiviral Agents. Drugs Used in Reproductive Endocrinology. Nicotine Preparations in Smoking. Systemic Drugs for Skin Diseases. Topical Liposome Drugs. Topical Glucocorticoids. Index.

    Notă biografică

    Korting, Hans C. | Schafer-Korting, M.

    Descriere

    This handbook provides the reader with a more comprehensive look at various facets of benefit-to-risk ratio assessment. It also provides the clinician with data allowing optimization of his decisions on drug treatment.