The Carnitine System: A New Therapeutical Approach to Cardiovascular Diseases: Developments in Cardiovascular Medicine, cartea 162
Editat de J. W. de Jong, R. Ferrarien Limba Engleză Paperback – 11 ian 2012
Although several books on carnitine have been published, a treatise focusing on experimental and clinical aspects of the carnitine family and cardiovascular diseases was lacking. The present book provides the reader with a concise update in this field. The information collected from experts on various aspects of the fascinating compound, carnitine, will be useful for both clinicians and basic scientists.
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Specificații
ISBN-13: 9789401041225
ISBN-10: 9401041229
Pagini: 416
Ilustrații: 400 p. 33 illus.
Dimensiuni: 160 x 240 x 22 mm
Greutate: 0.58 kg
Ediția:Softcover reprint of the original 1st ed. 1995
Editura: SPRINGER NETHERLANDS
Colecția Springer
Seria Developments in Cardiovascular Medicine
Locul publicării:Dordrecht, Netherlands
ISBN-10: 9401041229
Pagini: 416
Ilustrații: 400 p. 33 illus.
Dimensiuni: 160 x 240 x 22 mm
Greutate: 0.58 kg
Ediția:Softcover reprint of the original 1st ed. 1995
Editura: SPRINGER NETHERLANDS
Colecția Springer
Seria Developments in Cardiovascular Medicine
Locul publicării:Dordrecht, Netherlands
Public țintă
ResearchCuprins
1. Introduction.- One: The carnitine system in the heart: molecular aspects.- 2. Carnitine-dependent pathways in heart muscle.- 3. Carnitine and carnitine esters in mitochondrial metabolism and function.- 4. The effects of carnitine on myocardial carbohydrate metabolism.- 5. Accumulation of fatty acids and their carnitine derivatives during myocardial ischemia.- 6. Carnitine acylcarnitine translocase in ischemia.- 7. Amphiphilic interactions of long-chain fatty acylcarnitines with membranes: potential involvement in ischemic injury.- 8. Mitochondrial injury in the ischemic-reoxygenated cardiomyocyte: the role of lipids and other pathogenic factors.- 9. Free radical-mediated damage and carnitine esters.- 10. Carnitine transport in volume-overloaded rat hearts.- 11. Myocardial carnitine deficiency in human cardiomyopathy.- Two: Therapeutic efficacy of L-carnitine at the myocardial level.- 12. Is the carnitine system part of the heart antioxidant network?.- 13. Experimental evidence of the anti-ischemic effect of L-carnitine.- 14. Carnitine metabolism during diabetes and hyperthyroidy.- 15. Carnitine and lactate metabolism.- 16. Therapeutic potential of L-carnitine in patients with angina pectoris.- 17. Carnitine and myocardial infarction.- Three: Therapeutic efficacy of propionyl-L-carnitine.- 18. Cardiac electrophysiology of propionyl-L-carnitine.- 19. Acute vs. chronic treatment with propionyl-L-carnitine: biochemical, hemodynamic and electrophysiological effects on rabbit heart.- 20. Mechanical recovery with propionyl-L-carnitine.- 21. Dissociation of hemodynamic and metabolic effects of propionyl-L-carnitine in ischemic pig heart.- 22. Effect of propionyl-L-carnitine on rats with experimentally induced cardiomyopathies.- 23. Utilization of propionyl-L-carnitine for the treatment of heart failure.- 24. Hemodynamic and metabolic effect of propionyl-L-carnitine in patients with heart failure.- 25. Carnitine metabolism in peripheral arterial disease.- 26. Effect of propionyl-L-carnitine on experimental models of peripheral arteriopathy in the rat.- 27. Effect of L-carnitine and propionyl-L-carnitine on cardiovascular diseases: a summary.